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Impact Factor : 8.14

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Paper Title: Role of Intravascular Imaging and Intravascular Lithotripsy in the Management of Complex Calcific Coronary Lesions: A Case Report
Authors Name: Mr. Syed Nazar Raza , Naziya Yasmin , Gazala Naqvi
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Published Paper Id: IJRTI2605168
Published In: Volume 11 Issue 5, May-2026
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Abstract: Background: Heavily calcified coronary artery disease (CAD) represents one of the most technically demanding challenges in interventional cardiology, as calcium deposits limit appropriate lesion preparation and adequate stent expansion. Case Presentation: We report the case of a 56-year-old male with double-vessel disease involving critical stenosis of the proximal left anterior descending artery (LAD) and mid-to-distal right coronary artery (RCA). Percutaneous coronary intervention (PCI) was performed under dual-modality intravascular imaging guidance using the Makoto near-infrared spectroscopy and intravascular ultrasound (NIRS-IVUS) system. Intravascular lithotripsy (IVL) was employed for calcium modification prior to drug-eluting stent (DES) deployment. Results: NIRS-IVUS revealed circumferential calcium arcs up to 360° in the proximal LAD with concealed lipid-rich plaque [maxLCBI₄mm = 788], and a mixed calcific-fibrotic lesion in the mid-RCA [maxLCBI₄mm = 249]. Following IVL and DES deployment, post-intervention imaging demonstrated a minimal stent area (MSA) of 5.6 mm² in the LAD and 3.6–5.3 mm² across RCA segments, with LCBI₄mm scores reduced to 486 and 106, respectively. Conclusion: This case underscores the complementary value of NIRS-IVUS imaging and IVL-assisted lesion preparation in achieving optimal stent outcomes in complex calcific coronary lesions. The detection of lipid-rich plaque concealed beneath calcium using NIRS provided clinical insights that IVUS alone could not offer.
Keywords: intravascular ultrasound, near-infrared spectroscopy, intravascular lithotripsy, calcific coronary artery disease, percutaneous coronary intervention, drug-eluting stent
Cite Article: "Role of Intravascular Imaging and Intravascular Lithotripsy in the Management of Complex Calcific Coronary Lesions: A Case Report", International Journal for Research Trends and Innovation (www.ijrti.org), ISSN:2456-3315, Vol.11, Issue 5, page no.b610-b613, May-2026, Available :http://www.ijrti.org/papers/IJRTI2605168.pdf
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ISSN: 2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
Publication Details: Published Paper ID: IJRTI2605168
Registration ID:212964
Published In: Volume 11 Issue 5, May-2026
DOI (Digital Object Identifier):
Page No: b610-b613
Country: new delhi, delhi, India
Research Area: Medical Science
Publisher : IJ Publication
Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2605168
Published Paper PDF: https://www.ijrti.org/papers/IJRTI2605168
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ISSN: 2456-3315
Impact Factor: 8.14 and ISSN APPROVED, Journal Starting Year (ESTD) : 2016

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