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International Journal for Research Trends and Innovation
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ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
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Volume 11 | Issue 6
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Impact Factor : 8.14
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Volume Published : 11
Issue Published : 121
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| Paper Title: | Design and Evaluation of Compact High-Voltage Pulse Generators: From Piezoelectric Architectures to Sustainable E-Waste Multipliers |
| Authors Name: | Udit Singh , Sunil Kumawat , Akshat Jindal , Rajeev Kapoor |
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IJRTI_212866
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| Published Paper Id: | IJRTI2605149 |
| Published In: | Volume 11 Issue 5, May-2026 |
| DOI: | |
| Abstract: | Medical electroporation involves the use of short duration, high voltage electric pulses to transiently permeabilize biological cells by increased membrane permeability for targeted delivery of chemotherapeutic drugs or genetic material. Standard high-voltage pulse generators for electroporation, developed using magnetic coupled DC-DC converter, are large and produce high levels of electromagnetic interference (EMI) and are limited by core saturation. This paper explores and presents two alternative approaches to implementation of small high-voltage generator. Architecture I showcases state of the art theory of solid state design (using a Piezoelectric Transformer (PT)) in the context of high-precision, magnetic-free, high-voltage step-up circuitry from a 24V DC source, powered by Wide Band Gap (WBG) Semiconductors (GaN/SiC). Architecture II provides an integrated solution which responds to the growing constraints of real-world power-supply logistics and exorbitant procurement costs by presenting a conservative, manufacturable, near-term solution to attaining aspirational voltages in a fully functional, repurposed form factor. This decoupled architecture builds on the dual strengths of an asynchronous flyback oscillator and a series of cascade-connected Cockcroft-Walton voltage multipliers constructed entirely out of repurposed e-waste ferrite cores. The repurposed and integrated flyback multiplier power supply is extensively simulated (LTSpice and QSPICE) and experimentally verified via spark-gap measures to reliably supply 3,000V with extremely limited set of accessible discrete components from a miniature 3.7V Lithium-ion source. A dualistic, principle-driven approach of what can be adopted and what should be adopted results in a holistic solution integrating the most powerful aspects of high-end biomedical power electronics in practical, sustainable frameworks. |
| Keywords: | Electroporation, Piezoelectric Transformer, Wide-Bandgap Semiconductors, Cockcroft-Walton Multiplier, E Waste Repurposing, High-Voltage Pulse Generator |
| Cite Article: | "Design and Evaluation of Compact High-Voltage Pulse Generators: From Piezoelectric Architectures to Sustainable E-Waste Multipliers", International Journal for Research Trends and Innovation (www.ijrti.org), ISSN:2456-3315, Vol.11, Issue 5, page no.b429-b433, May-2026, Available :http://www.ijrti.org/papers/IJRTI2605149.pdf |
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| ISSN: |
2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID: IJRTI2605149
Registration ID:212866
Published In: Volume 11 Issue 5, May-2026
DOI (Digital Object Identifier):
Page No: b429-b433 Country: Delhi, New Delhi, India Research Area: Electronics & Communication Engg. Publisher : IJ Publication Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2605149 Published Paper PDF: https://www.ijrti.org/papers/IJRTI2605149 |
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ISSN: 2456-3315
Impact Factor: 8.14 and ISSN APPROVED,
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