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International Journal for Research Trends and Innovation
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ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
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Issue: June 2026
Volume 11 | Issue 6
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Impact Factor : 8.14
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| Paper Title: | Formulation and evaluation of potassium iodide gummies for the prevention of iodine deficiency disorders. |
| Authors Name: | Divyesh Prashant Gahivad , Lokesh Devidas Chaudhari , Harish Devidas Bodhare , Dr. Swapnil Dilip Deo |
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IJRTI_212893
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| Published Paper Id: | IJRTI2605147 |
| Published In: | Volume 11 Issue 5, May-2026 |
| DOI: | |
| Abstract: | Iodine deficiency is one of the most prevalent micronutrient deficiency disorders worldwide and is associated with serious health complications such as goiter, hypothyroidism, impaired cognitive development, and cretinism. Although iodized salt and conventional iodine supplements are widely used, factors such as iodine loss during cooking and storage, poor patient compliance, unpleasant taste, and swallowing difficulties limit their effectiveness. Therefore, there is a need to develop an alternative, patient-friendly dosage form that can improve iodine supplementation and therapeutic acceptability. The present study was aimed at the formulation and evaluation of potassium iodide-loaded pharmaceutical gummies as a novel drug delivery system for iodine supplementation. Three formulations (F1, F2, and F3) were prepared using potassium iodide as the active pharmaceutical ingredient along with gelatin and agar-agar as gelling agents. Additional excipients such as sugar, glucose syrup, citric acid, sodium benzoate, flavouring agent, and colouring agent were incorporated to improve texture, palatability, and stability. The prepared gummies were evaluated for organoleptic properties, weight variation, pH, moisture content, texture analysis, content uniformity, disintegration/chewing time, thickness, and stability studies. The results demonstrated that all formulations possessed acceptable physicochemical characteristics and patient-friendly properties. Among the prepared formulations, F2 exhibited the most desirable characteristics including optimum texture, lower moisture content, excellent drug content uniformity, better chewability, and improved stability profile. The study concluded that potassium iodide medicated gummies can serve as a promising and effective alternative to conventional dosage forms for iodine supplementation, particularly in pediatric and geriatric populations, by improving patient compliance, palatability, and ease of administration. |
| Keywords: | Potassium iodide, Iodine deficiency disorders, pharmaceutical gummies, Novel drug delivery system, Medicated gummies, Goiter, Patient compliance, Iodine supplementation, Gelatin, Thyroid hormones |
| Cite Article: | "Formulation and evaluation of potassium iodide gummies for the prevention of iodine deficiency disorders.", International Journal for Research Trends and Innovation (www.ijrti.org), ISSN:2456-3315, Vol.11, Issue 5, page no.b388-b422, May-2026, Available :http://www.ijrti.org/papers/IJRTI2605147.pdf |
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2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID: IJRTI2605147
Registration ID:212893
Published In: Volume 11 Issue 5, May-2026
DOI (Digital Object Identifier):
Page No: b388-b422 Country: Chatrapati Sambhaji Nagar, Maharashtra, India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2605147 Published Paper PDF: https://www.ijrti.org/papers/IJRTI2605147 |
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ISSN: 2456-3315
Impact Factor: 8.14 and ISSN APPROVED,
Journal Starting Year (ESTD) : 2016
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