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Bacterial-borne infections pose a serious threat in tropical and subtropical regions, and with rising resistance issues, effective control has become a pressing concern. This study explores the synthesis of magnesium oxide (MgO) nanoparticles using four innovative methods: green synthesis, microwave-assisted synthesis, sol-gel and hydrothermal techniques. The resulting MgO nanoparticles were characterized via FT-IR (Fourier Transform Infrared Spectroscopy), XRD (X-ray Diffraction), SEM (Scanning Electron Microscopy), and EDAX (Energy-Dispersive X-ray Analysis). FT-IR confirmed the presence of functional groups, while XRD and HRSEM unveiled structural and morphological details. EDAX validated the elemental composition, highlighting Mg and O.
Antibacterial efficacy was tested against Gram-positive bacteria (Enterococcus faecalis) and. Among the three synthesis methods, hydrothermally synthesized MgO nanoparticles at 50 mg/mL exhibited the highest activity—producing zones of inhibition (ZOI) of 7 mm for E. faecalis showed the greatest sensitivity, with a 9 mm ZOI using sol-gel-produced MgO.
Further, antioxidant activity was tested against synthesized MgO nanostructures proved most effective, achieving a great Antioxidant (SOD) of unit 15.558 unit/mg , while green-synthesized variants showed the lowest (11.493 unit/mg). These findings position MgO nanostructures as promising dual-function agents for both antibacterial therapy and Antioxidant properties.
Keywords:
Magnesium nanoparticles, Antibacterial activity and Anti-oxidant activity
Cite Article:
"Magnesium Oxide Nanoparticles: Potent Antibacterial and Antioxidant Nanostructures", International Journal for Research Trends and Innovation (www.ijrti.org), ISSN:2455-2631, Vol.11, Issue 1, page no.b188-b199, January-2026, Available :http://www.ijrti.org/papers/IJRTI2601124.pdf
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ISSN:
2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator