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International Journal for Research Trends and Innovation
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ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
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Issue: February 2026
Volume 11 | Issue 2
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Impact Factor : 8.14
Issue per Year : 12
Volume Published : 11
Issue Published : 117
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| Paper Title: | Biochemical Profiling of Syzygium cumini (Jamun) Pulp Extract: Evaluation of Hypolipidemic Efficacy, Hepato-Renal Safety, and Antioxidant Homeostasis in Mus musculus |
| Authors Name: | Ganesh Fadake , Pratiksha Mhalsane |
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IJRTI_209232
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| Published Paper Id: | IJRTI2601064 |
| Published In: | Volume 11 Issue 1, January-2026 |
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| Abstract: | Syzygium cumini, commonly known as Jamun, is a fruit with significant medicinal properties. It is abundant in polyphenols, flavonoids, and anthocyanins, which are recognised for their role in regulating metabolic and oxidative processes. This study aimed to assess the hypolipidemic effects, liver and kidney safety, and antioxidant capabilities of S. cumini pulp extract in healthy mice (Mus musculus). Jamun fruits were sourced from the Buldhana district in Maharashtra, India, and underwent methanolic cold extraction. Thirty male mice received oral doses of the extract at 200 and 400 mg/kg body weight for 28 days. The results showed a notable dose-dependent decrease (P < 0.05) in total cholesterol, triglyceride, and low-density lipoprotein (LDL) levels, along with an increase in high-density lipoprotein (HDL). Liver enzymes (ALT and AST) and kidney markers (creatinine and urea) remained within the normal physiological range, indicating no toxicity. Increased superoxide dismutase (SOD) activity and decreased malondialdehyde (MDA) levels demonstrated an improved antioxidant balance. These findings confirm the safety and metabolic regulatory potential of S. cumini pulp extract, supporting its development as a functional nutraceutical agent. |
| Keywords: | Keywords: Syzygium cumini, hypolipidemic activity, antioxidant enzymes, hepato-renal safety, Mus musculus |
| Cite Article: | "Biochemical Profiling of Syzygium cumini (Jamun) Pulp Extract: Evaluation of Hypolipidemic Efficacy, Hepato-Renal Safety, and Antioxidant Homeostasis in Mus musculus", International Journal for Research Trends and Innovation (www.ijrti.org), ISSN:2455-2631, Vol.11, Issue 1, page no.a456-a459, January-2026, Available :http://www.ijrti.org/papers/IJRTI2601064.pdf |
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| ISSN: |
2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID: IJRTI2601064
Registration ID:209232
Published In: Volume 11 Issue 1, January-2026
DOI (Digital Object Identifier):
Page No: a456-a459 Country: Bramhanchikna, Maharashtra( महाराष्ट्र ), India Research Area: Science & Technology Publisher : IJ Publication Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2601064 Published Paper PDF: https://www.ijrti.org/papers/IJRTI2601064 |
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ISSN: 2456-3315
Impact Factor: 8.14 and ISSN APPROVED,
Journal Starting Year (ESTD) : 2016
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