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As per 2023 data, India has the 2nd largest HIV epidemic in the world(6.3% of the global PLHIV). National prevalence among adult population remains low(0.20%). India has significantly reduced the annual incidence by 44.23%(global decline-38%) between 2010-2023 and deaths have declined by 79.26%(global decline-51%). Though the country shows a low adult prevalence, its 9-43 times increased among high-risk groups. This is mainly attributable to factors like increased intravenous drug abusers in North Eastern states, increased female sex workers in Southern states, larger and denser urbanized areas, stigma and lack of awareness, and disparities among the states with respect to HIV testing, treatment and prevention strategies. The situational analysis identified an increase in HIV prevalence among the key and vulnerable population when compared to the national average. NACO has also reported 144 high burden districts in India with a prevalence of >1% in 2019. Among the key population with PLHIV, the ART coverage varies between 28-58.7% Knowledge about HIV prevention practices was reported to be 26.17%. Hence, PrEP can be considered as an additional effort to the existing services to end the epidemic by 2030. Hence, this study explains an approach to the use of lenacapavir for pre-exposure prophylaxis in high-risk groups in high-burden districts of India
Keywords:
NACO, ART, PLHIV, PrEP, lenacapavir
Cite Article:
"Situational analysis of HIV in India and approach to the use of lenacapavir for pre-exposure prophylaxis in high-risk groups", International Journal for Research Trends and Innovation (www.ijrti.org), ISSN:2455-2631, Vol.10, Issue 9, page no.b110-b114, September-2025, Available :http://www.ijrti.org/papers/IJRTI2509114.pdf
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ISSN:
2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator