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International Journal for Research Trends and Innovation
International Peer Reviewed & Refereed Journals, Open Access Journal
ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
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Issue: December 2025
Volume 10 | Issue 12
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Impact Factor : 8.14
Issue per Year : 12
Volume Published : 10
Issue Published : 115
Article Submitted : 19551
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Total Authors : 21317
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| Paper Title: | Nanoemulgels: A Promising Drug Delivery System for Enhanced Therapeutic Efficacy |
| Authors Name: | Rushali S. Koli , Dr. Sujit kakade , Dr. Ashok Bhosale |
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IJRTI_202405
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| Published Paper Id: | IJRTI2504127 |
| Published In: | Volume 10 Issue 4, April-2025 |
| DOI: | |
| Abstract: | The lipophilic nature of many newly developed drugs often leads to poor bioavailability and variability in pharmacokinetics, necessitating the development of novel delivery systems. Among these, nanoemulgel, a transdermal delivery system, has shown promise in improving the systemic delivery and therapeutic profile of lipophilic drugs. This formulation outperforms conventional oral and topical drug delivery methods by minimizing disturbances and enhancing drug stability, bioavailability, and therapeutic efficacy. Nanoemulgel combine nanoemulsions, which contain the drug, with a gel base, creating a non-greasy, highly viscous, and stable formulation. The finely distributed oil droplets within the gel significantly enhance the skin permeability of the incorporated drug, making it an effective topical delivery system. This method targets the drug to peripheral sites of action, bypassing first-pass metabolism and overcoming gastric system incompatibilities. This review evaluates the potential and future prospects of nanoemulgel formulations as effective delivery systems for poorly water-soluble drugs. It covers methods of preparation, component screening, formulation strategies, and recent advancements in pharmacokinetic and pharmacodynamics properties, as evidenced by global research studies. The findings indicate that nanoemulgels represent a significant advancement in drug delivery technology, particularly for enhancing the systemic delivery and therapeutic profile of lipophilic drug. |
| Keywords: | Nanoemulgel; Nanoemulsion; Topical drug delivery; Pharmacokinetics; Pharmacodynamics |
| Cite Article: | "Nanoemulgels: A Promising Drug Delivery System for Enhanced Therapeutic Efficacy ", International Journal of Science & Engineering Development Research (www.ijrti.org), ISSN:2455-2631, Vol.10, Issue 4, page no.b214-b228, April-2025, Available :http://www.ijrti.org/papers/IJRTI2504127.pdf |
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| ISSN: |
2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID: IJRTI2504127
Registration ID:202405
Published In: Volume 10 Issue 4, April-2025
DOI (Digital Object Identifier):
Page No: b214-b228 Country: pune, maharashtra, India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2504127 Published Paper PDF: https://www.ijrti.org/papers/IJRTI2504127 |
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ISSN: 2456-3315
Impact Factor: 8.14 and ISSN APPROVED,
Journal Starting Year (ESTD) : 2016
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