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International Journal for Research Trends and Innovation
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ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
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Impact Factor : 8.14
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| Paper Title: | VALIDATED HPLC METHOD FOR ANALYSIS OF REMOGLIFLOZIN ETABONATE IN TABLETS |
| Authors Name: | MUBEEN G , NISAR AHMED , TASMIYA SULTANA , LALITHA N , VYSHNAVI A |
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IJRTI_200077
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| Published Paper Id: | IJRTI2501049 |
| Published In: | Volume 10 Issue 1, January-2025 |
| DOI: | |
| Abstract: | A RP-HPLC method has been developed and validated for determination of Remogliflozin etabonate in bulk and pharmaceutical formulation. It was performed on Phenomenex Hyper clone column 5µm BDS C18-250 ×4.6 mm using Acetonitrile and water in the ratio of 80:20 as mobile phase at a flow rate of 1ml/min and analytes were monitored at 228 nm. The retention time for Remogliflozin etabonate was found to be 4.88 min. The peak obtained was symmetrical with tailing factor less than 1.5 and theoretical plates more than 2000. The developed method was validated in accordance to ICH guidelines and the results of all parameters was found to be within the acceptable limits. The linearity was found in the concentration range of 1-500μg/mL, LOD and LOQ was found to be 0.694 and 2.313μg/mL for Remogliflozin etabonate. The percentage Mean recovery at three different levels (80%, 100% and 120%) was found to be 100.71 %w/w and the % Assay for Remogliflozin etabonate in tablets was found to be 99.6 %w/w. The developed method has been found suitable for routine analysis of Remogliflozin etabonate in bulk and formulation (tablet). |
| Keywords: | Remogliflozin etabonate, RP-HPLC, ICH Guidelines |
| Cite Article: | "VALIDATED HPLC METHOD FOR ANALYSIS OF REMOGLIFLOZIN ETABONATE IN TABLETS", International Journal of Science & Engineering Development Research (www.ijrti.org), ISSN:2455-2631, Vol.10, Issue 1, page no.a383-a390, January-2025, Available :http://www.ijrti.org/papers/IJRTI2501049.pdf |
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2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID: IJRTI2501049
Registration ID:200077
Published In: Volume 10 Issue 1, January-2025
DOI (Digital Object Identifier):
Page No: a383-a390 Country: BANGLORE, KARNATAKA, INDIA Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2501049 Published Paper PDF: https://www.ijrti.org/papers/IJRTI2501049 |
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ISSN: 2456-3315
Impact Factor: 8.14 and ISSN APPROVED,
Journal Starting Year (ESTD) : 2016
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