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Impact Factor : 8.14

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Paper Title: Assessment of Adverse Drug Reactions (ADRs) in Inpatients at a Tertiary Care Hospital in Bangalore - A Prospective study
Authors Name: Dhirendra yadav , Krishna kumar mahato , Balakeshwa Ramaiah
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IJRTI_188721
Published Paper Id: IJRTI2312077
Published In: Volume 8 Issue 12, December-2023
DOI:
Abstract: Abstract Background: Globallly it is identified that adverse drug reactions (ADRs) are prime cause of morbidity and motality. In sequence to reduce suffering it is necessary to observe this kind of adverse effect with great attention and report. Early reporting of suspected adverse effect to regulatory authorities is proper means of ensuring public health and safety from adverse drug reactions of such drugs. Objective: In this interventional study ADRs were detected, assessed and reported in a tertiary care hospital. Also analyze the pattern of predictability, severity, causality and preventability of occurrence of ADRs at a tertiary care hospital. Method: This observational study conducted for a period of six months. Data were collected from inpatient departments. Collected data were evaluated on the basis of different parameters like predictability of each ADR was assessed by using the system introduced by Wills and Brown classification, severity by Hartwig and Siegel scale, causality by WHO-ADR scale and preventability by modified Schumock and Thornton scale. Results: A total of 259 ADRs were listed over 6 months ; highest number of ADRs observed in male. Approximately, 136 patients (58.87 %) experienced adverse drug reactions during hospital stay. According to Naranjo’s causality assessment criteria showed that maximum number of ADRs were probable(72% ) followed by definite(18%) and possible(10%). According To Will's And Brown classification the most common type of adverse drug reaction reported were type B 97 (37%) followed by type A 95 (37%). The WHO-UMC criteria showed that 72% were probable and 18% were certain in nature. Modified Thornton And Schumock's Preventability Assessment Scale showed that 90% were not preventable ADRs. Modified Hartwig Severity assessment scale accounted that maximum number of ADRs were (54%) moderate followed by mild (41%) and severe (5%). Interpretation and Conclusion: Regular monitoring of ADRs helps in minimization/prevention of ADRs, as well as reduce economical burden and also improves drug adherence , quality of life and clinical outcome in patients. Data obtained from this study provides knowledge about future drug selection, risk benefit assessment in drug therapy.
Keywords: Unavoidable, ADRs, WHO, Minimization, Knowledge, Assessment
Cite Article: "Assessment of Adverse Drug Reactions (ADRs) in Inpatients at a Tertiary Care Hospital in Bangalore - A Prospective study", International Journal of Science & Engineering Development Research (www.ijrti.org), ISSN:2455-2631, Vol.8, Issue 12, page no.548 - 558, December-2023, Available :http://www.ijrti.org/papers/IJRTI2312077.pdf
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ISSN: 2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
Publication Details: Published Paper ID: IJRTI2312077
Registration ID:188721
Published In: Volume 8 Issue 12, December-2023
DOI (Digital Object Identifier):
Page No: 548 - 558
Country: Bangalore urban, karnataka, India
Research Area: Pharmacy
Publisher : IJ Publication
Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2312077
Published Paper PDF: https://www.ijrti.org/papers/IJRTI2312077
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ISSN: 2456-3315
Impact Factor: 8.14 and ISSN APPROVED, Journal Starting Year (ESTD) : 2016

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