IJRTI
International Journal for Research Trends and Innovation
International Peer Reviewed & Refereed Journals, Open Access Journal
ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.14 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI)

Call For Paper

For Authors

Forms / Download

Published Issue Details

Editorial Board

Other IMP Links

Facts & Figure

Impact Factor : 8.14

Issue per Year : 12

Volume Published : 11

Issue Published : 117

Article Submitted : 21311

Article Published : 8476

Total Authors : 22301

Total Reviewer : 802

Total Countries : 156

Indexing Partner

Licence

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License
Published Paper Details
Paper Title: NIOSOMES: A REVIEW OF THEIR STRUCTURE, PROPERTIES, METHODS OF PREPARATION, AND MEDICAL APPLICATIONS
Authors Name: Jayashri Suresh Borole , Dr. Atul R. Bendale , Dr. Sushil patil , Dr. Laxmikant Borse
Download E-Certificate: Download
Author Reg. ID:
IJRTI_186597
Published Paper Id: IJRTI2305069
Published In: Volume 8 Issue 5, May-2023
DOI:
Abstract: Drug targeting is a type of phenomenon in which a drug is distributed in the body in such a way that the drug interacts with the target tissue at the cellular or subcellular level to achieve the desired therapeutic response at the desired site without unwanted interactions at other sites. This can be achieved by modern methods of drug delivery system targeting such as niosomes. Niosomes are a type of non-ionic surfactant vesicles that are biodegradable, non-toxic, more stable and cheaper, which is a new approach to liposomes. Their structure is similar to liposomes and therefore they may represent alternative vesicular systems to liposomes. Niosomes tend to load different types of drugs. This review article presents niosome structure, advantages, disadvantages, niosome preparation methods and characterization of pharmaceutical NSVs. The concept of a drug delivery system refers to the process of administering pharmaceutical compounds at a predetermined rate to achieve a therapeutic effect in humans or animals at the site of disease while simultaneously reducing the concentration of the drug in surrounding tissues. The localized action of the drug increases the effectiveness of the drug and reduces systemic toxic effects on tissues. Paul Ehrlich proposed the idea of targeted delivery directly to a diseased cell without harming healthy cells in 1909, and this strategy was known as the "magic bullet". Since then, a variety of drug carrier systems have emerged, including immunoglobulins, serum proteins, synthetic polymers, liposomes, microspheres, and niosomes. Among these systems, liposomes and niosomes are well- documented vesicular drug delivery systems. In general, a vesicular system is a drug delivery platform that enables efficient bioavailability of drugs through the controlled release of therapeutic drugs over extended periods of time. Vesicles consist of bilayered amphiphilic molecules that surround an aqueous compartment. Niosomes are vesicles of nonionic surfactant (for example, alkyl ester and alkyl ether) and cholesterol that act as a carrier for amphiphilic and lipophilic drugs. Niosomes improve the therapeutic efficacy of encapsulated drug molecules by protecting the drug from the harsh biological environment, resulting in their delayed clearance New drug development is both time- consuming and expensive.
Keywords: Niosomes, Liposomes, Non-ionic surfactants, Drug delivery, Nanocarriers, Encapsulation technology
Cite Article: "NIOSOMES: A REVIEW OF THEIR STRUCTURE, PROPERTIES, METHODS OF PREPARATION, AND MEDICAL APPLICATIONS", International Journal for Research Trends and Innovation (www.ijrti.org), ISSN:2455-2631, Vol.8, Issue 5, page no.441 - 447, May-2023, Available :http://www.ijrti.org/papers/IJRTI2305069.pdf
Downloads: 000205280
ISSN: 2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
Publication Details: Published Paper ID: IJRTI2305069
Registration ID:186597
Published In: Volume 8 Issue 5, May-2023
DOI (Digital Object Identifier):
Page No: 441 - 447
Country: Nhavi, MAHARASHTRA, India
Research Area: Pharmacy
Publisher : IJ Publication
Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2305069
Published Paper PDF: https://www.ijrti.org/papers/IJRTI2305069
Share Article:

Click Here to Download This Article

Article Preview
Click Here to Download This Article

Major Indexing from www.ijrti.org
Google Scholar ResearcherID Thomson Reuters Mendeley : reference manager Academia.edu
arXiv.org : cornell university library Research Gate CiteSeerX DOAJ : Directory of Open Access Journals
DRJI Index Copernicus International Scribd DocStoc

ISSN Details

ISSN: 2456-3315
Impact Factor: 8.14 and ISSN APPROVED, Journal Starting Year (ESTD) : 2016

DOI (A digital object identifier)


Providing A digital object identifier by DOI.ONE
How to Get DOI?

Conference

Open Access License Policy

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License

Creative Commons License This material is Open Knowledge This material is Open Data This material is Open Content

Important Details

Join RMS/Earn 300

IJRTI

WhatsApp
Click Here

Indexing Partner