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International Journal for Research Trends and Innovation
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ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
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Impact Factor : 8.14
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| Paper Title: | Stability indicating RP-HPLC Method Development & Validation For Simultaneous of Mirabegron & Solifenacin succinate In Tablet Dosage Form |
| Authors Name: | Priyanshi M. Patel , Mr. Jaymin G. Patel , Mr. Kaushik R. Patel , Ms. Janki A. Patel , Ms. Bhumi R. Patel |
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IJRTI_185694
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| Published Paper Id: | IJRTI2303103 |
| Published In: | Volume 8 Issue 3, March-2023 |
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| Abstract: | Simple, rapid, economical, precise and accurate Stability indicating RP- HPLC method for the estimation of Mirabegron and Solifenacin succinate in Tablet Dosage Form has been developed.A reverse phase high performance liquid chromatographic method was developed for the estimation of Mirabegron and Solifenacin succinate in Tablet Dosage Form has been developed. The separation was achieved Column Kromasil C18 (150 x 4.6) 5 µm ID, Gradient program 0.1%Triethylamine in water pH adjusted 3.0 with OPA: Acetonitrile, as mobile phase, at a flow rate of 1 ml/min. Detection was carried out at 225 nm retention time of MR and SOL was found to be 4.547 and 4.548 min. The method has been validated for linearity, accuracy and precision. Linearity observed for Solifenacin succinate and Mirabegron 25.10-373.50 μg/ml. Developed method was found to be accurate, precise and rapid for estimation of Mirabegron and Solifenacin succinate in Tablet Dosage Form. The drug was subjected to stress condition of hydrolysis, oxidation, photolysis and Thermal degradation, under same chromatographic condition. The stress samples were assayed on RP-HPLC system. |
| Keywords: | Mirabegron, Solifenacin succinate, Stability indicating RP- HPLC Method, Validation. |
| Cite Article: | "Stability indicating RP-HPLC Method Development & Validation For Simultaneous of Mirabegron & Solifenacin succinate In Tablet Dosage Form", International Journal of Science & Engineering Development Research (www.ijrti.org), ISSN:2455-2631, Vol.8, Issue 3, page no.586 - 596, March-2023, Available :http://www.ijrti.org/papers/IJRTI2303103.pdf |
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2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID: IJRTI2303103
Registration ID:185694
Published In: Volume 8 Issue 3, March-2023
DOI (Digital Object Identifier):
Page No: 586 - 596 Country: Ahmedabad, Gujarat, India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2303103 Published Paper PDF: https://www.ijrti.org/papers/IJRTI2303103 |
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ISSN: 2456-3315
Impact Factor: 8.14 and ISSN APPROVED,
Journal Starting Year (ESTD) : 2016
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