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International Journal for Research Trends and Innovation
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ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
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Impact Factor : 8.14
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| Paper Title: | FORMULATION AND EVALUATION OF ORAL CONTROLLED RELEASE TABLETS OF OXYBUTYNIN |
| Authors Name: | Mr. Permula Praveen Kumar , Mrs. M. Shiroja , Mr.Chandrasekhara Rao Baru , Miss .Guddanti Hema , Mrs. Beebireddy Vidhya |
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IJRTI_184228
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| Published Paper Id: | IJRTI2210048 |
| Published In: | Volume 7 Issue 10, October-2022 |
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| Abstract: | ABSTRACT The objective of the study was to develop matrix tablets of oral controlled release tablets of oxybutynin. In the present study oxybutynin tablets were successfully developed using direct compression method. To achieve better patient compliance and for prolonged release of drug from the dosage form. Formulation development of diffusion based tablets of oxybutynin using different types of polymers such as Ethyl cellulose, Chitosan, and Locust bean gum and selection of the best formulation among them. Flow properties Angle of repose, Loose bulk density ,tapped density and also Carr’s index was determined for all the formulations which showed good flow property. The thickness found uniform, ,hardness and friability values of all the formulations tablets prepared by direct compression method were within the limits and found to be mechanically stable .In vitro dissolution results showed that% of drug release was prolonged in formulation F5 that is up to 12hrs when compared to other formulations .This indicates the drug released from the formulation F5 was effective up to 12 hours . Oxybutynin is used to treat certain bladder and urinary conditions Oxybutynin belongs to a class of drugs known as antispasmodics. Oxybutynin is indicated for the symptomatic treatment of overactive bladder, which causes urge urinary incontinence and frequency, and urgency. Oxybutynin may also be used for children aged 6 and above for the symptomatic management of detrusor muscle overactivity which has been found to be related to a neurological condition. |
| Keywords: | Prolonged release of drug, patient compliance, symptomatic treatment of overactive bladder |
| Cite Article: | "FORMULATION AND EVALUATION OF ORAL CONTROLLED RELEASE TABLETS OF OXYBUTYNIN", International Journal of Science & Engineering Development Research (www.ijrti.org), ISSN:2455-2631, Vol.7, Issue 10, page no.362 - 365, October-2022, Available :http://www.ijrti.org/papers/IJRTI2210048.pdf |
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2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID: IJRTI2210048
Registration ID:184228
Published In: Volume 7 Issue 10, October-2022
DOI (Digital Object Identifier):
Page No: 362 - 365 Country: HYDERABAD, TELANGANA, India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2210048 Published Paper PDF: https://www.ijrti.org/papers/IJRTI2210048 |
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ISSN: 2456-3315
Impact Factor: 8.14 and ISSN APPROVED,
Journal Starting Year (ESTD) : 2016
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