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The spherules in addition provides an opportunity to modify its surface properties by polymer film coating. It improves the functional properties such as appearance, drug release and integrity of particles during processing of spherules. Also the spherules have low surface area to volume ratio so less amount of coating solution is required. Granules and pellets shape is not necessarily spherical in nature. Coated spherules can also be an option for coating instead of coating the tablet. Instead of the tablet coated spherules help in reducing the disintegration time of the tablet. It can also help in the reducing the manufacturing cost of the final tablet as coating, spheronization & drying can be occur at the same time which also help in reducing the time of manufacturing .
Keywords:
Propranolol , Lactose ,MCC ,PVP
Cite Article:
"Formulation and evaluation of coated spherules ", International Journal of Science & Engineering Development Research (www.ijrti.org), ISSN:2455-2631, Vol.7, Issue 8, page no.206 - 210, August-2022, Available :http://www.ijrti.org/papers/IJRTI2208033.pdf
Downloads:
000202503
ISSN:
2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
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