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Objective: Aim of this study is to formulate and evaluate Cinnamic Acidmicroemulsion-
basedgel for topical use to reduce hyperpigmentation.
Methods: The gel was prepared using oleic acid as oil phase, tween 80 as a surfactant,
propylene glycol as co-surfactant, carbopol 934 as a gelling age,ntand distilled water as the
aqueousphase. Then, skin pH (6.5-7) was maintained by dropwise addition of
triethanolamine. Then the prepared microemulsion-based gel was characterized for pH,
spreadability, viscosity, and in vitro studies.
Results: Results indicated that the gel showed good appearance, homogeneity, and
spreadability. Viscosity is between 34720 ± 1254 centipoises. The in vitro release studies
also indicated that the formulation was of desirable release pattern
Keywords:
In the present study, a satisfactory attempt was made to formulate a microemulsion-based gel of Cinnamic Acid and acceptable for topical delivery.
Cite Article:
"Formulation and evaluation of microemulsion based gel for hyperpigmentation", International Journal for Research Trends and Innovation (www.ijrti.org), ISSN:2455-2631, Vol.7, Issue 6, page no.1720 - 1734, July-2022, Available :http://www.ijrti.org/papers/IJRTI2206257.pdf
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ISSN:
2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator