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For the successful treatment of dermatophytoses, there is a need for accurate and rapid diagnostic methods. Dermatophytosis is caused by fungi from the Epidermophyton, Microsporum, and Trichophyton genera. Dermatophytes are keratinophilic (keratin-digesting) fungi that can cause disease. Human and animal pathogens are Microsporum and Trichophyton species, however Epidermophyton is an obligatory human pathogen. The present investigation was aimed to study the isolation of dermatophytes and it’s molecular characterization by using Multiplex PCR in tertiary care hospital. According to the current analysis using the microtube dilution technique, antifungal sensitivity testing for dermatophytic isolates revealed that terbinafine is a more sensitive agent for therapy and fluconazole is going towards resistance. Multiplex PCR is a useful method for identifying dermatophyte isolates since it is quick and easy to use. When compared to morphological and biochemical features, molecular approaches such as multiplex PCR improve the specificity of dermatophytosis laboratory diagnosis.
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Cite Article:
"To study the isolation of dermatophytes and it’s molecular characterization by using Multiplex PCR in tertiary care hospital", International Journal for Research Trends and Innovation (www.ijrti.org), ISSN:2455-2631, Vol.7, Issue 6, page no.198 - 203, June-2022, Available :http://www.ijrti.org/papers/IJRTI2206035.pdf
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ISSN:
2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator