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Introduction: Preeclampsia is a common complication of pregnancy associated with increased morbidity and mortality in mother and fetus. During pregnancy there is an increased demand and synthesis of thyroid hormones. Thyroid Hormones plays a role in Placental development and is an important regulator of various metabolic and Inflammatory process. Aim: To compare the thyroid hormone level in severe, moderate, mild preeclamptic woman with normal pregnant woman. Materials and methods: A total of 60 subjects aged 25-40 years were selected from Antenatal clinic, Department of obstetrics and Gynecology, Gandhi Hospital, Secunderabad. Thyroid profile was analyzed by chemiluminiscence immunoassay. Results: The mean and S.D of serum TSH in cases is 5.6± 4.4 as compared to 3.7 ± 1.9 in controls p value 0.008 and pearson correlation 0.33 which is considered highly significant. The mean and S.D of serum T3 in controls is 1.77 ± 0.64 as compared to 1.65 ± 0.6 in cases. The mean and S. D of serum T4 in controls is 9.5 ± 2.7 as compared to 11.6 ± 4.06. Conclusion: Screening of thyroid profile should be done in all pregnant women to identify thyroid abnormalities and to prevent severity of morbidity and mortality associating with preeclampsia.
Keywords:
Thyroid disorders, Hypothyroidism, T3, T4 and TSH.
Cite Article:
"A COMPARATIVE STUDY OF THYROID HORMONE LEVELS IN PREECLAMPTIC WOMEN AND NORMAL PREGNANT WOMEN ", International Journal for Research Trends and Innovation (www.ijrti.org), ISSN:2455-2631, Vol.7, Issue 6, page no.121 - 125, June-2022, Available :http://www.ijrti.org/papers/IJRTI2206023.pdf
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000205277
ISSN:
2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator