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International Journal for Research Trends and Innovation
International Peer Reviewed & Refereed Journals, Open Access Journal
ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
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Issue: June 2026
Volume 11 | Issue 6
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Impact Factor : 8.14
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| Paper Title: | Clinical Pearls of Choosing the Right Semaglutide Brand in Diabetes: Indian Real-world Case Series |
| Authors Name: | Anusha Handral , Dr. Karunesh Kumar H S , Dr. Abhishek Arun |
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IJRTI_212725
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| Published Paper Id: | IJRTI2605124 |
| Published In: | Volume 11 Issue 5, May-2026 |
| DOI: | |
| Abstract: | Background: Glucagon-like peptide-1 receptor agonists (GLP-1 RAs), such as semaglutide, play a pivotal role in helping patients manage type 2 diabetes mellitus (T2DM) and obesity by improving glycemic control, supporting weight reduction, and enhancing appetite regulation. With the recent launch of generic semaglutide brands, clinicians now have multiple prescribing options. There are currently no real-world case studies of switching among these brands in India. Methods: We present four Indian real-world case reports involving patients with T2DM and/or weight issues who were transitioned between semaglutide brands. Key clinical parameters, patient-reported outcomes, treatment adherence, and device usability were assessed before and after the switchover, with short-term follow-up. Results: In these cases, switching between semaglutide brands was associated with clinically relevant challenges, including differences in efficacy, gastrointestinal tolerability, appetite control, device usability, and treatment adherence. These differences contributed to early variations in glycemic control, body weight, and caregiver support dependence in some patients. In all these cases, patients expressed a preference for the reference semaglutide brand (Ozempic® or Rybelsus®), citing greater tolerability, better control, familiarity, and ease of use. Conclusion: These cases highlight the clinical significance of brand-related and device-related factors in determining therapeutic outcomes with semaglutide. Careful consideration of patients’ experience, device familiarity, and close monitoring following treatment switches helps optimise adherence and clinical efficacy in routine Indian clinical practice. |
| Keywords: | Glucagon-like peptide-1 receptor agonists, semaglutide, type 2 diabetes mellitus, obesity, weight loss, Ozempic®, Rybelsus® |
| Cite Article: | "Clinical Pearls of Choosing the Right Semaglutide Brand in Diabetes: Indian Real-world Case Series", International Journal for Research Trends and Innovation (www.ijrti.org), ISSN:2456-3315, Vol.11, Issue 5, page no.b165-b172, May-2026, Available :http://www.ijrti.org/papers/IJRTI2605124.pdf |
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2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID: IJRTI2605124
Registration ID:212725
Published In: Volume 11 Issue 5, May-2026
DOI (Digital Object Identifier):
Page No: b165-b172 Country: Bengaluru, Karnataka , India Research Area: Health Science Publisher : IJ Publication Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2605124 Published Paper PDF: https://www.ijrti.org/papers/IJRTI2605124 |
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ISSN: 2456-3315
Impact Factor: 8.14 and ISSN APPROVED,
Journal Starting Year (ESTD) : 2016
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