ISSN2456-3315
Impact Factor10.57
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ESTD2016
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Paper Title
Analytical method developemtn and validation for simultaneous estimation of API in pharmaceutical dosage form by using RP-HPLC method
Authors
Pranali Gajanan Ravekar , S. G.Jawarkar
Keywords
Vonoprazan, reverse phase high performance liquid chromatography, amoxicillin analysis, tablets
Abstract
A simple, specific and sensitive reverse phase high performance liquid chromatographic method was developed and validated for simultaneous determination of vonoprazan and amoxicillin from pharmaceutical dosage forms. The method uses Hypersil, C18 (250mm x 4.6ID, Particle size: 5 um) column and isocratic elution. The mobile phase composed of MeOH:Water:Glacial acetic acid, at the ratio of 75:24.5:0.5 v/v was used at a flow rate of 1.0 ml /min. UV detector was programmed at 232 nm for first 10 min and at 244 nm for 10 to 20 min. All the validation parameters were in acceptable range. The developed method was effectively applied to quantitate amount of vonoprazan and amoxicillin from tablets. The method was also applied suitably for determining the degradation products of vonoprazan and amoxicillin .
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IJRTI — journal style
"Analytical method developemtn and validation for simultaneous estimation of API in pharmaceutical dosage form by using RP-HPLC method", IJRTI - International Journal for Research Trends and Innovation (www.ijrti.org), ISSN:2456-3315, Vol.10, Issue 8, page no.a600-a609, August-2025, Available :https://ijrti.org/papers/IJRTI2508074.pdf
APA — 7th edition
Ravekar, P. G., & G.Jawarkar, S. (2025). Analytical method developemtn and validation for simultaneous estimation of API in pharmaceutical dosage form by using RP-HPLC method. International Journal for Research Trends and Innovation, 10(8), a600-a609. https://ijrti.org/viewpaperforall.php?paper=IJRTI2508074
MLA — 9th edition
Ravekar, Pranali Gajanan, and S. G.Jawarkar. "Analytical method developemtn and validation for simultaneous estimation of API in pharmaceutical dosage form by using RP-HPLC method." International Journal for Research Trends and Innovation, vol. 10, no. 8, 2025, pp. a600-a609, https://ijrti.org/viewpaperforall.php?paper=IJRTI2508074.
Chicago — 17th, bibliography
Ravekar, Pranali Gajanan, and S. G.Jawarkar. "Analytical method developemtn and validation for simultaneous estimation of API in pharmaceutical dosage form by using RP-HPLC method." International Journal for Research Trends and Innovation 10, no. 8 (2025): a600-a609. https://ijrti.org/viewpaperforall.php?paper=IJRTI2508074.
Harvard — author–date
Ravekar, P.G. and G.Jawarkar, S. (2025) 'Analytical method developemtn and validation for simultaneous estimation of API in pharmaceutical dosage form by using RP-HPLC method', International Journal for Research Trends and Innovation, 10(8), pp. a600-a609. Available at: https://ijrti.org/viewpaperforall.php?paper=IJRTI2508074
IEEE — numbered reference
P. G. Ravekar and S. G.Jawarkar, "Analytical method developemtn and validation for simultaneous estimation of API in pharmaceutical dosage form by using RP-HPLC method," IJRTI, vol. 10, no. 8, pp. a600-a609, Aug. 2025.
Vancouver — biomedical
Ravekar PG, G.Jawarkar S. Analytical method developemtn and validation for simultaneous estimation of API in pharmaceutical dosage form by using RP-HPLC method. IJRTI. 2025 Aug;10(8):a600-a609.
AMA — 11th edition
Ravekar PG, G.Jawarkar S. Analytical method developemtn and validation for simultaneous estimation of API in pharmaceutical dosage form by using RP-HPLC method. IJRTI. 2025;10(8):a600-a609. Accessed at https://ijrti.org/viewpaperforall.php?paper=IJRTI2508074
BibTeX — Zotero, Mendeley, LaTeX
@article{IJRTI2508074,
author = {Pranali Gajanan Ravekar and S. G.Jawarkar},
title = {Analytical method developemtn and validation for simultaneous estimation of API in pharmaceutical dosage form by using RP-HPLC method},
journal = {International Journal for Research Trends and Innovation},
volume = {10},
number = {8},
pages = {a600-a609},
year = {2025},
month = {August},
issn = {2456-3315},
url = {https://ijrti.org/viewpaperforall.php?paper=IJRTI2508074}
}
RIS — EndNote, RefWorks
TY - JOUR
AU - Ravekar, Pranali Gajanan
AU - G.Jawarkar, S.
TI - Analytical method developemtn and validation for simultaneous estimation of API in pharmaceutical dosage form by using RP-HPLC method
T2 - International Journal for Research Trends and Innovation
JA - IJRTI
VL - 10
IS - 8
PY - 2025
SN - 2456-3315
UR - https://ijrti.org/viewpaperforall.php?paper=IJRTI2508074
SP - a600-a609
ER -
Issue
Volume 10 Issue 8,
August-2025
Pages : a600-a609
Other Publication Details
Paper Reg. ID
IJRTI_205258
Published Paper ID
IJRTI2508074
Downloads
205,669
Research Area
Pharmacy
Country
amravati, Maharashtra, India
Published
August 2025
Published Paper PDF
https://ijrti.org/papers/IJRTI2508074.pdf
Published Paper URL
https://ijrti.org/viewpaperforall.php?paper=IJRTI2508074
About Publisher
International Journal for Research Trends and Innovation
Published by IJRTI (JW Publication)
2456-3315
ISSN
10.57
Impact Factor
2016
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Open
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Impact Factor 10.57 calculated by Google Scholar and Semantic Scholar.
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Declarations
Funding
No external funding was received for this study.
Conflict of Interest
The authors declare that they have no conflict of interest.
Acknowledgements
The authors would like to thank the reviewers and the editorial board of International Journal for Research Trends and Innovation for their careful reading and constructive comments, and all colleagues who supported the preparation of this manuscript.
