 |
International Journal for Research Trends and Innovation
International Peer Reviewed & Refereed Journals, Open Access Journal
ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.14 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI)
|
Issue: March 2026
Volume 11 | Issue 3
Review Result and Publication of Paper within : 2-3 days
Click Here For more DetailsFor Authors
Forms / Download
Published Issue Details
Editorial Board
Other IMP Links
Facts & Figure
Impact Factor : 8.14
Issue per Year : 12
Volume Published : 11
Issue Published : 118
Article Submitted : 21653
Article Published : 8541
Total Authors : 22459
Total Reviewer : 811
Total Countries : 159
Indexing Partner
Licence
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License
|
Published Paper Details
|
|
| Paper Title: | Exploring the Potential of Ganoderma Lucidum in Cancer Treatment: Benefits and Limitation of its Biological Actions |
| Authors Name: | Aditya Ranjan Jena , J Anbu , S Deepika , Yuvarani K R , M Srujana |
| Download E-Certificate: | Download |
| Author Reg. ID: |
IJRTI_205334
|
| Published Paper Id: | IJRTI2507091 |
| Published In: | Volume 10 Issue 7, July-2025 |
| DOI: | https://doi.org/10.56975/ijrti.v10i7.205334 |
| Abstract: | Ganoderma lucidum, a traditional Asian medicine with a long history, has been found to be a potential candidate in complementary cancer therapy. This review thoroughly discusses the anticancer potential of G. lucidum based on its bioactive compounds, mainly polysaccharides and triterpenoids, and their mechanistic functions. The mushroom has multifunctional activities, such as immune system modulation, apoptosis induction, cancer cell proliferation inhibition, metastasis and angiogenesis suppression, and oxidative stress regulation. Polysaccharides activate immune cells and cytokine production, which increases the host's antitumor activity. Triterpenoids, especially ganoderic acids, have direct cytotoxicity and modulate pathways like PI3K/Akt and MAPK. G. lucidum exerts synergistic action with chemotherapy and radiotherapy, enhancing the efficacy of treatments and minimizing side effects such as nausea and fatigue. In spite of its therapeutic potential, limitations including low bioavailability, unstandardized extract, and insufficient high-quality clinical trials limit its clinical use in the mainstream. Future studies must be directed towards nanoparticle-based drug delivery systems and standardized formulations to enhance efficacy and predictability. This review underscores the great potential of G. lucidum as both a treatment and prophylactic agent in oncology, which deserves further investigation and clinical testing. |
| Keywords: | Key-words: Ganoderma lucidum, cancer therapy, triterpenoids, PI3K/Akt |
| Cite Article: | "Exploring the Potential of Ganoderma Lucidum in Cancer Treatment: Benefits and Limitation of its Biological Actions", International Journal for Research Trends and Innovation (www.ijrti.org), ISSN:2455-2631, Vol.10, Issue 7, page no.a837-a851, July-2025, Available :http://www.ijrti.org/papers/IJRTI2507091.pdf |
| Downloads: | 000391 |
| ISSN: |
2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
| Publication Details: |
Published Paper ID: IJRTI2507091
Registration ID:205334
Published In: Volume 10 Issue 7, July-2025
DOI (Digital Object Identifier): https://doi.org/10.56975/ijrti.v10i7.205334
Page No: a837-a851 Country: Bengaluru, Karnataka, India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2507091 Published Paper PDF: https://www.ijrti.org/papers/IJRTI2507091 |
| Share Article: | |
|
Click Here to Download This Article |
|
| Article Preview | |
|
|
|
Major Indexing from www.ijrti.org
| Google Scholar | ResearcherID Thomson Reuters | Mendeley : reference manager | Academia.edu |
| arXiv.org : cornell university library | Research Gate | CiteSeerX | DOAJ : Directory of Open Access Journals |
| DRJI | Index Copernicus International | Scribd | DocStoc |
ISSN Details
 |
 |
|
ISSN: 2456-3315
Impact Factor: 8.14 and ISSN APPROVED,
Journal Starting Year (ESTD) : 2016
DOI (A digital object identifier)
| Providing A digital object identifier by DOI.ONE How to Get DOI? |
Conference
Open Access License Policy
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License
Important Details
Join RMS/Earn 300
WhatsApp
Click Here
Click Here
Indexing Partner |
|||
| Copyright © 2026 - All Rights Reserved - IJRTI | |||