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International Journal for Research Trends and Innovation
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ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
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| Paper Title: | Assessment of Treatment And Surgical Intervention For Diabetic Foot Ulcer |
| Authors Name: | ERAIANBU V , Dr.N.Junior Sundresh , Dr.S.Selvamuthukumar , SHAMINI S , SURIYAPRAKASH M |
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IJRTI_204878
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| Published Paper Id: | IJRTI2506149 |
| Published In: | Volume 10 Issue 6, June-2025 |
| DOI: | |
| Abstract: | Background: Diabetic foot ulcer (DFU) is one of the most common and severe complications associated with diabetes mellitus, leading to significant morbidity, risk of limb amputation, and increased healthcare costs. The condition results from a complex interplay of peripheral neuropathy, peripheral vascular disease, infection, and poor glycemic control. In India and other developing countries, delayed diagnosis, inadequate wound care, and limited access to multidisciplinary interventions contribute to poor outcomes. Early diagnosis and appropriate treatment—including both surgical and pharmacological strategies—are essential to reduce complications and improve healing. Given the high burden of DFUs in tertiary care settings, there is a critical need to assess and compare treatment modalities, particularly the role of surgical interventions and antibiotic regimens. Objectives: This study aimed to evaluate the effectiveness of different surgical and pharmacological treatments in the management of diabetic foot ulcers. The specific objectives were to (1) analyze the outcome of various surgical interventions, (2) assess wound healing, infection rates, and patient recovery, and (3) examine the cost-effectiveness of conservative versus invasive approaches in a tertiary care hospital setting. Methods: A prospective observational study was conducted over a six-month period (November 2023 to April 2024) at the Department of Surgery, Government Cuddalore Medical College and Hospital, Tamil Nadu, India. A total of 150 patients aged ≥18 years with chronic diabetic foot ulcers (≥4 weeks duration) were enrolled after applying inclusion and exclusion criteria. Data were collected using a structured proforma covering patient demographics, ulcer classification (Wagner Grade), duration of diabetes, ulcer location and duration, type of surgical intervention (debridement, amputation, dressing, conservative), and antibiotic treatment. Statistical analysis, including binary logistic regression, was used to identify significant predictors of healing outcomes. A p-value of <0.05 was considered statistically significant. Results: Among the 150 patients, 70.7% were male, with a mean age of 55.6 ± 10.2 years. Patients with unhealed ulcers were significantly older than those who healed (mean age 57.5 vs. 52.8 years, p = 0.015). Logistic regression analysis revealed that higher Wagner grades (OR = 5.58, p = 0.025) and surgical amputation (OR = 0.001, p < 0.001) were strong negative predictors of healing. Conversely, conservative interventions such as debridement and dressing, although not statistically significant, showed more favorable healing trends. The treatment model showed an overall accuracy of 84%, with high sensitivity (93.1%) for predicting non-healing outcomes. Antibiotic regimens, including cefotaxime, piperacillin-tazobactam, and linezolid, were commonly used, but their statistical influence on healing was limited. Conclusion: The study underscores that advanced age and higher Wagner grade are significant predictors of non-healing in DFUs. Conservative surgical approaches may lead to better healing outcomes compared to amputation. Multidisciplinary care, involving surgeons, pharmacists, and wound care specialists, is essential for effective DFU management. Early intervention, proper wound classification, and patient education are vital to improve outcomes and reduce recurrence. |
| Keywords: | Diabetic foot ulcer, Wagner classification, surgical debridement, amputation, conservative management, wound healing, pharmacy practice, logistic regression, antibiotic therapy, multidisciplinary care. |
| Cite Article: | "Assessment of Treatment And Surgical Intervention For Diabetic Foot Ulcer", International Journal for Research Trends and Innovation (www.ijrti.org), ISSN:2455-2631, Vol.10, Issue 6, page no.b391-b395, June-2025, Available :http://www.ijrti.org/papers/IJRTI2506149.pdf |
| Downloads: | 000475 |
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2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID: IJRTI2506149
Registration ID:204878
Published In: Volume 10 Issue 6, June-2025
DOI (Digital Object Identifier):
Page No: b391-b395 Country: CHIDAMBARAM, TAMILNADU, India Research Area: Medical Science Publisher : IJ Publication Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2506149 Published Paper PDF: https://www.ijrti.org/papers/IJRTI2506149 |
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