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The aim of the present study was formulation and evaluation nanostructured lipid carriers (NLCs) gel for topical delivery. Minoxidil (MXD) loaded nanostructured lipid carriers (NLCs) was prepared by using emulsion solvent diffusion and evaporation method followed by ultrasonication. The prepared NLCs was further characterized by SEM, particle size, zeta potential, entrapment efficiency, drug content and in-vitro diffusion study. on the basis of criteria, the drug diffused at 8 hr. the f6 batch is optimized and the optimized batch is incorporated in gel for further evaluation such as pH determination, drug content, viscosity and in-vitro diffusion study, stability. from the in-vitro diffusion study we observed that the Minoxidil release from NLCs gel by Higuchi model model indicates good linearity, which show controlled release of from Nanostructured Lipid Carriers gel.
Keywords:
Nanostructured Lipid Carriers, Androgenic Alopecia, Topical drug delivery system, Gel, SEM, Entrapment efficiency etc.
Cite Article:
"Formulation And Evaluation Of Nanostructured Lipid Carrier Loaded Gel For Topical Delivery. ", International Journal for Research Trends and Innovation (www.ijrti.org), ISSN:2455-2631, Vol.10, Issue 6, page no.b360-b372, June-2025, Available :http://www.ijrti.org/papers/IJRTI2506145.pdf
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ISSN:
2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator