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International Journal for Research Trends and Innovation
International Peer Reviewed & Refereed Journals, Open Access Journal
ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
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Impact Factor : 8.14
Issue per Year : 12
Volume Published : 11
Issue Published : 118
Article Submitted : 21664
Article Published : 8541
Total Authors : 22459
Total Reviewer : 811
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| Paper Title: | FORMULATION AND EVALUATION OF MICROSPONGES LOADED GEL FOR TOPICAL DELIVERY |
| Authors Name: | Tanvi S. Kokate , Dr.Vikrant P. Wankhade , Vikram V. Bhoyar , Neha S. Ghogare |
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IJRTI_204754
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| Published Paper Id: | IJRTI2506100 |
| Published In: | Volume 10 Issue 6, June-2025 |
| DOI: | |
| Abstract: | The present research focuses on the formulation and evaluation of a microsponge-based topical gel containing Karanjin for the treatment of skin conditions such as psoriasis. Microsponges were prepared using the quasi-emulsion solvent diffusion technique with ethyl cellulose and polyvinyl alcohol as key polymers. The formulated microsponges were characterized in terms of particle size, production yield, and encapsulation efficiency. The optimized microsponge formulation was incorporated into a Carbopol 940-based gel and evaluated for physical properties including pH, viscosity, spreadability, and drug content. In vitro, diffusion studies and release kinetics were conducted using a Franz diffusion cell, and the formulation followed Korsmeyer-Peppas release behavior. The optimized gel demonstrated sustained drug release, good stability, and effective potential for topical delivery. The study concludes that the microsponge-loaded gel system provides a promising approach for enhanced therapeutic efficacy and controlled release of Karanjin through the skin. |
| Keywords: | Microsponges, Psoriasis, Topical Drug Delivery, Controlled Release, Gel Formulation, Quasi-emulsion Solvent Diffusion. |
| Cite Article: | "FORMULATION AND EVALUATION OF MICROSPONGES LOADED GEL FOR TOPICAL DELIVERY ", International Journal for Research Trends and Innovation (www.ijrti.org), ISSN:2455-2631, Vol.10, Issue 6, page no.a866-a876, June-2025, Available :http://www.ijrti.org/papers/IJRTI2506100.pdf |
| Downloads: | 000470 |
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2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID: IJRTI2506100
Registration ID:204754
Published In: Volume 10 Issue 6, June-2025
DOI (Digital Object Identifier):
Page No: a866-a876 Country: Amravati, Maharashtra, India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2506100 Published Paper PDF: https://www.ijrti.org/papers/IJRTI2506100 |
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ISSN: 2456-3315
Impact Factor: 8.14 and ISSN APPROVED,
Journal Starting Year (ESTD) : 2016
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