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International Journal for Research Trends and Innovation
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ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
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Impact Factor : 8.14
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| Paper Title: | Comparative evaluation of open flap debridement with and without intra-marrow penetration in the treatment of horizontal defects in Stage II and Stage III Grade B Periodontitis- A Randomized Controlled Trial |
| Authors Name: | Dr.Tulsi Tarase , Dr. Nupur Sah , Dr. Prashasti Sarode |
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IJRTI_203063
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| Published Paper Id: | IJRTI2506060 |
| Published In: | Volume 10 Issue 6, June-2025 |
| DOI: | |
| Abstract: | Background: Periodontal horizontal bone loss remains a challenging entity in regenerative therapy. Open Flap Debridement (OFD) is an established surgical modality; however, its outcomes in horizontal defects are often limited. Intra Marrow Penetration (IMP) has been proposed as an adjunct to enhance bone regeneration through stimulation of the regional acceleratory phenomenon. Aim: To evaluate and compare the clinical and radiographic outcomes of Open Flap Debridement with and without Intra Marrow Penetration in the treatment of horizontal bone defects in Stage II and Stage III Grade B Periodontitis patients. Materials and Methods: A randomized, split-mouth clinical trial was conducted on 10 systemically healthy subjects aged 30-60 years, involving 30 bilateral sites exhibiting horizontal bone loss. Site A received OFD with IMP, and Site B received OFD alone. Clinical parameters including Plaque Index (PI), Gingival Index (GI), Probing Pocket Depth (PPD), and Clinical Attachment Level (CAL) were evaluated at baseline, 3 months, and 6 months. Radiographic defect depth and defect fill percentage were assessed using standardized intraoral periapical radiographs at baseline and 6 months. Results: Both groups exhibited significant improvements in clinical parameters over time. However, Site A (OFD + IMP) demonstrated greater reductions in PPD, greater CAL gain, and a higher percentage of radiographic defect fill compared to Site B (OFD alone), with statistically significant differences at 6 months. Conclusion: Intra Marrow Penetration as an adjunct to Open Flap Debridement significantly enhances clinical and radiographic outcomes in the treatment of horizontal defects in Stage II and III Grade B Periodontitis. This simple and cost-effective technique could offer improved therapeutic predictability for horizontal periodontal bone defects. Keywords: Horizontal bone loss, Open Flap Debridement, Intra Marrow Penetration, Periodontitis, Defect Fill, Clinical Attachment Level. |
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| Cite Article: | "Comparative evaluation of open flap debridement with and without intra-marrow penetration in the treatment of horizontal defects in Stage II and Stage III Grade B Periodontitis- A Randomized Controlled Trial", International Journal for Research Trends and Innovation (www.ijrti.org), ISSN:2455-2631, Vol.10, Issue 6, page no.a533-a539, June-2025, Available :http://www.ijrti.org/papers/IJRTI2506060.pdf |
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2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID: IJRTI2506060
Registration ID:203063
Published In: Volume 10 Issue 6, June-2025
DOI (Digital Object Identifier):
Page No: a533-a539 Country: Thane, Maharashtra , India Research Area: Health Science Publisher : IJ Publication Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2506060 Published Paper PDF: https://www.ijrti.org/papers/IJRTI2506060 |
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ISSN: 2456-3315
Impact Factor: 8.14 and ISSN APPROVED,
Journal Starting Year (ESTD) : 2016
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