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International Journal for Research Trends and Innovation
International Peer Reviewed & Refereed Journals, Open Access Journal
ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
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Impact Factor : 8.14
Issue per Year : 12
Volume Published : 11
Issue Published : 118
Article Submitted : 21686
Article Published : 8549
Total Authors : 22487
Total Reviewer : 811
Total Countries : 159
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| Paper Title: | Formulation and Evaluation of Orodispersible Film |
| Authors Name: | Aditya Santosh Kakad , Dr. Nitin S. Bhajipale , Prof. Harish K. Kunjwani |
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| Author Reg. ID: |
IJRTI_204236
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| Published Paper Id: | IJRTI2505286 |
| Published In: | Volume 10 Issue 5, May-2025 |
| DOI: | |
| Abstract: | The present research focuses on the formulation and evaluation of orodispersible films (ODFs) of Granisetron, an antiemetic agent, designed to enhance patient compliance and provide rapid therapeutic action. Orodispersible films offer a convenient and effective drug delivery system, particularly beneficial for pediatric, geriatric, and dysphagic patients. In this study, various formulations were developed using the solvent casting method, employing hydroxypropyl methylcellulose as the primary film-forming polymer along with suitable plasticizers and excipients to ensure desirable mechanical properties and rapid disintegration. The prepared films were evaluated for physical appearance, thickness, weight uniformity, folding endurance, disintegration time, drug content, and in-vitro dissolution profile. Among all formulations, the batch F5 exhibited optimal performance, demonstrating rapid disintegration and enhanced drug release, making it a promising candidate for improving bioavailability and onset of action. This investigation highlights the potential of orodispersible films as a patient-friendly alternative to conventional dosage forms for the management of nausea and vomiting. |
| Keywords: | Orodispersible film, Mouth dissolving film |
| Cite Article: | "Formulation and Evaluation of Orodispersible Film", International Journal for Research Trends and Innovation (www.ijrti.org), ISSN:2455-2631, Vol.10, Issue 5, page no.c734-c741, May-2025, Available :http://www.ijrti.org/papers/IJRTI2505286.pdf |
| Downloads: | 000463 |
| ISSN: |
2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID: IJRTI2505286
Registration ID:204236
Published In: Volume 10 Issue 5, May-2025
DOI (Digital Object Identifier):
Page No: c734-c741 Country: Buldhana, Maharashtra, India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2505286 Published Paper PDF: https://www.ijrti.org/papers/IJRTI2505286 |
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ISSN: 2456-3315
Impact Factor: 8.14 and ISSN APPROVED,
Journal Starting Year (ESTD) : 2016
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