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ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
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Impact Factor : 8.14

Issue per Year : 12

Volume Published : 11

Issue Published : 118

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Paper Title: FORMULATION, ANALYTICAL METHOD DEVELOPMENT AND VALIDATION OF ANTI-ARTHRITIS DRUGS BY HPLC METHOD
Authors Name: Prasad A. Badukale , Vijay M. Waghulkar , Monika P. Jadhao
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IJRTI_204142
Published Paper Id: IJRTI2505244
Published In: Volume 10 Issue 5, May-2025
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Abstract: This disquisition paper presents the development and evidence of a High- Performance Liquid Chromatography( HPLC) system for the estimation of Piroxicam and Esomeprazole, both of which are significant medicinal used in pain operation and gastric acid storing inhibition, singly. The study details the regular approach taken to establish a reliable logical system, including the characterization of the drugs, solubility studies, selection of chromatographic conditions, and the drug of mobile phases. The optimized HPLC system was validated in agreement with ICH guidelines for parameters including particularity, delicacy, perfection, linearity, limit of discovery, and robustness. The system demonstrated satisfactory performance characteristics, including a high degree of particularity and linearity across a wide attention range. The developed HPLC system is presented as a simple, rapid-fire- fire, and cost-effective logical tool suitable for routine quantitative and qualitative analysis of Piroxicam and Esomeprazole in pharmaceutical phrasings. The findings support the system’s operation within the pharmaceutical sedulity, enhancing the quality control processes for these essential specifics.
Keywords: High- Performance Liquid Chromatography (HPLC), Piroxicam, Esomeprazole, Method Development and Validation, Tablet
Cite Article: "FORMULATION, ANALYTICAL METHOD DEVELOPMENT AND VALIDATION OF ANTI-ARTHRITIS DRUGS BY HPLC METHOD", International Journal for Research Trends and Innovation (www.ijrti.org), ISSN:2455-2631, Vol.10, Issue 5, page no.c378-c388, May-2025, Available :http://www.ijrti.org/papers/IJRTI2505244.pdf
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ISSN: 2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
Publication Details: Published Paper ID: IJRTI2505244
Registration ID:204142
Published In: Volume 10 Issue 5, May-2025
DOI (Digital Object Identifier):
Page No: c378-c388
Country: Amravati, Maharashtra, India
Research Area: Pharmacy
Publisher : IJ Publication
Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2505244
Published Paper PDF: https://www.ijrti.org/papers/IJRTI2505244
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ISSN: 2456-3315
Impact Factor: 8.14 and ISSN APPROVED, Journal Starting Year (ESTD) : 2016

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