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International Journal for Research Trends and Innovation
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ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
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Impact Factor : 8.14
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| Paper Title: | Evaluation of long-term bleeding risk with anticoagulant usage in patients diagnosed with atrial fibrillation: A prospective and observational study |
| Authors Name: | Dr. Ravinder M , Dr. Shibi mary thomas , Dr. Balakeshwa Ramaiah |
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| Author Reg. ID: |
IJRTI_200066
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| Published Paper Id: | IJRTI2412030 |
| Published In: | Volume 9 Issue 12, December-2024 |
| DOI: | http://doi.one/10.1729/Journal.42750 |
| Abstract: | Aim: To study & evaluate the long-term risk of bleeding in patients taking oral anticoagulants diagnosed with atrial fibrillation. Methodology: A prospective and observational study was conducted in the departments of cardiology and medicine, involving patients who met specific inclusion criteria. Data collected included demographic details (age, sex) from patient charts, physician notes, and interviews. Information on drug usage, such as names, doses, routes of administration, and duration, was recorded, along with relevant laboratory data. The treatment chart was reviewed for additional drugs that could cause bleeding. Interviews were conducted with patients or family members to gather information on previous strokes, bleeding complications, or incidents after starting anticoagulant therapy. NSAID use during follow-ups was also documented. All follow-up data was preserved to maintain patient privacy. RESULTS: The study involved 50 patients over six months, with a mean age of 66.6 years. 64% of patients were over 65 years old, and there were 27 males and 23 females. Common risk factors for atrial fibrillation (AF) included hypertension (35 patients) and diabetes mellitus (23 patients). Symptoms were most frequently dyspnea (42%), oedema (30%), palpitations and giddiness (24%), chest pain and orthopnea (16%), and syncope (6%). Interestingly, 22% of patients had no symptoms. Among the patients, 12% were smokers, and 14% were alcoholics. Of the 47 patients who underwent ECHO, 77% had a normal left ventricular ejection fraction (50-75%), while 23% had reduced ejection fraction (<50%). Half of the patients had a normal heart rate (<100 bpm). For anticoagulation therapy, 32% received rivaroxaban, 26% apixaban, 14% acitrom, 4% dabigatran, and 2% warfarin. 22% of patients were not prescribed any anticoagulants. The mean duration of anticoagulant therapy was 13 months. Additionally, 34% were prescribed an antiplatelet for stroke prevention, and 66% received heart rate-controlling drugs alongside oral anticoagulants (OAC). Using the CHADVaSC score for stroke risk, 8% of patients had a score of 0, 6% had a score of 1, 14% had a score of 2, 14% had a score of 3, 22% had a score of 4, 22% had a score of 5, 10% had a score of 6, and 4% had a score of 7. The HAS-BLED score for bleeding risk showed 12% with a score of 0, 20% with a score of 1, 16% with a score of 2, 28% with a score of 3, 18% with a score of 4, 4% with a score of 5, and 2% with a score of 6. Of the 50 patients, 3 experienced bleeding events, and 9 had strokes. Conclusion: The rate of major bleeding complications may be kept acceptably low in very elderly AF patients on OAT, provided careful anticoagulation management is obtained. This study concludes that there are less incidence of bleeding complications associated with the therapy in compared to the stroke occurrence. |
| Keywords: | Atrial fibrillation, Anticoagulant, Acitrom, Apixaban, Dabigatran, Rivaroxaban, Warfarin |
| Cite Article: | "Evaluation of long-term bleeding risk with anticoagulant usage in patients diagnosed with atrial fibrillation: A prospective and observational study", International Journal for Research Trends and Innovation (www.ijrti.org), ISSN:2455-2631, Vol.9, Issue 12, page no.a270-a291, December-2024, Available :http://www.ijrti.org/papers/IJRTI2412030.pdf |
| Downloads: | 000664 |
| ISSN: |
2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
| Publication Details: |
Published Paper ID: IJRTI2412030
Registration ID:200066
Published In: Volume 9 Issue 12, December-2024
DOI (Digital Object Identifier): http://doi.one/10.1729/Journal.42750
Page No: a270-a291 Country: Bangalore urban, Karnataka, India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2412030 Published Paper PDF: https://www.ijrti.org/papers/IJRTI2412030 |
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ISSN: 2456-3315
Impact Factor: 8.14 and ISSN APPROVED,
Journal Starting Year (ESTD) : 2016
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