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An autoimmune condition known as rheumatoid arthritis (RA) is characterized by joint and bone degradation. Current anti-inflammatory chemotherapeutic medications have negative side effects but provide momentary relief. Herbal remedies have demonstrated beneficial impact on RA symptoms with little side effects. In this work, we used in vitro methods to examine potential of Nyctanthes arbor-tristis and Cinamon bark. Alkaloids, polysaccharides, glycosides, phenolic compounds, peptides, free amino acids, and triterpenes were among the constituents that were qualitatively examined in methanolic extract of plants. HPTLC and TLC analyze substances that are active in extract. Extract show greatest scavenging properties in anti-arthritic action at 100 μg/mL. Anti-inflammatory activity investigate by following methods, such as protein denaturation, membrane destabilization and protease inhibitor method.
Keywords:
rheumatoid arthritis, anti-inflammatory, protein denaturation, methanolic extract
Cite Article:
"In vitro Investigations on the Anti-Arthritic Characteristics of Cinnamon Bark and NYCTANTHES ARBOR-TRISTIS", International Journal of Science & Engineering Development Research (www.ijrti.org), ISSN:2455-2631, Vol.9, Issue 7, page no.86 - 92, July-2024, Available :http://www.ijrti.org/papers/IJRTI2407008.pdf
Downloads:
000204761
ISSN:
2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator