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International Journal for Research Trends and Innovation
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ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
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Impact Factor : 8.14
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| Paper Title: | PHARMACOLOGICAL INVESTIGATION STUDIES OF ETHANOLIC PLANT EXTRACTS OF PHOENIX DACTYLIFERA AND YUCCA ALOIFOLIA IN THROMBOSIS AND INFLAMMATION USING K-CARRAGEENEAN ANIMAL MODEL |
| Authors Name: | Dr. Mehnoor Farheen , Zeba Begum , Amatul Tahoora , Duriya Muneer |
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IJRTI_188343
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| Published Paper Id: | IJRTI2311003 |
| Published In: | Volume 8 Issue 11, November-2023 |
| DOI: | |
| Abstract: | This study aimed to investigate the potential antithrombosis and anti-inflammatory properties of Phoenix dactylifera (date palm) and Yucca aloifolia (Spanish bayonet) extracts using K-Carrageenan-induced animal models.The objective was to assess the effects of these plant extracts on various biochemical parameters associated with inflammation, oxidative stress, coagulation, and immune responses.Wistar rats were divided into six groups, each containing six animals. The experimental design involved the administration of different substances, including normal saline, thrombotic control, toxic control with standard control, and toxic control with varying doses of plant extracts. The dosing schedule continued for 21 days, with subsequent blood sample collection for biochemical analysis. Acute inflammation was induced using carrageenan, and various parameters, such as malondialdehyde (MDA) levels, hemoglobin levels, edema progression, C-reactive protein (CRP) levels, bleeding time, clotting time, leukocyte count, platelet count, and thrombus length, were assessed. Both Phoenix dactylifera and Yucca aloifolia extracts demonstrated significant anti-inflammatory potential in the experimental animal models. They exhibited beneficial effects on MDA levels, hemoglobin levels, edema progression, CRP levels, bleeding time, clotting time, leukocyte count, platelet count, and thrombus length. These findings suggest that Phoenix dactylifera and Yucca aloifolia may have therapeutic applications in managing inflammatory conditions. |
| Keywords: | bleeding time, clotting time, leukocyte count, platelet count, inflammatory conditions, Phoenix dactylifera and Yucca aloifolia |
| Cite Article: | "PHARMACOLOGICAL INVESTIGATION STUDIES OF ETHANOLIC PLANT EXTRACTS OF PHOENIX DACTYLIFERA AND YUCCA ALOIFOLIA IN THROMBOSIS AND INFLAMMATION USING K-CARRAGEENEAN ANIMAL MODEL", International Journal of Science & Engineering Development Research (www.ijrti.org), ISSN:2455-2631, Vol.8, Issue 11, page no.15 - 31, November-2023, Available :http://www.ijrti.org/papers/IJRTI2311003.pdf |
| Downloads: | 000205178 |
| ISSN: |
2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID: IJRTI2311003
Registration ID:188343
Published In: Volume 8 Issue 11, November-2023
DOI (Digital Object Identifier):
Page No: 15 - 31 Country: -, -, India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2311003 Published Paper PDF: https://www.ijrti.org/papers/IJRTI2311003 |
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ISSN: 2456-3315
Impact Factor: 8.14 and ISSN APPROVED,
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