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Background
Burn injury is trauma with a high risk of infection. Debridement is a method that can be used to prevent and decrease the incidence of infection and accelerate wound healing. To minimize surgical site infection, the use of prophylactic antibiotics was considered in debridement.
Objective
The main objective of this study was to characterize the usage of prophylactic antibiotics for debridement in burn patients, including the selection, dose, and route of administration. The other objective was to quantitatively calculate the use of prophylactic antibiotics using ATC/DDD. (Anatomical therapeutic chemical/Defined Daily Dose)
Method
This was a retrospective study in burn patients admitted to the Government Cuddalore Medical College (GCMC), Chidambaram between 2019 and 2022.100 burn patients meet the inclusion criteria enrolled in this study. There were three prophylactic antibiotics used for debridement in this study. All prophylactic antibiotics were given intravenously.
The most common prophylactic antibiotics were ceftriaxone, meropenem, cefoperazone. Cefoperazone, and meropenem were used as therapeutic antibiotics to treat burn infection and continued as prophylactic before debridement surgery. ceftriaxone and cefoperazone were the most antibiotics that comply their dose with the guideline.
Result
Out of the total of (Defined Daily Dose) DDD/100 operations ceftriaxone was the highest consumed.
The mortality rate in our study was very less. For those who survived, there was a significant correlation between % TBSA and length of stay also debridement frequency.
Conclusion
Our study concluded that there was decrease in the infection and mortality rate after the administration of prophylactic antibiotics in debridement surgery for burn patients but improvements were needed to use prophylactic antibiotics more precisely regarding quantity and choice of the type of antibiotics.
"Use of prophylactic antibiotics for debridement surgery in burn patients – A retrospective surveillance", International Journal of Science & Engineering Development Research (www.ijrti.org), ISSN:2455-2631, Vol.8, Issue 2, page no.317 - 321, February-2023, Available :http://www.ijrti.org/papers/IJRTI2302051.pdf
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ISSN:
2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator