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International Journal for Research Trends and Innovation
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ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
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Impact Factor : 8.14
Issue per Year : 12
Volume Published : 11
Issue Published : 118
Article Submitted : 21513
Article Published : 8514
Total Authors : 22401
Total Reviewer : 805
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| Paper Title: | INVITRO AND INVIVO PHARMACOLOGICAL MODELS FOR THROMBOLYTIC ACTIVITY IN HYMENAEA MARTIANA AND GILLARDIA PULCHELLA ETHANOLIC EXTRACTS USING K-CARRAGEENAN INDUCED THROMBOSIS |
| Authors Name: | DR MEHNOOR FARHEEN , Afrose Fatima , Aqsa amtul , Ajmeri Begum |
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IJRTI_184728
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| Published Paper Id: | IJRTI2212014 |
| Published In: | Volume 7 Issue 12, December-2022 |
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| Abstract: | Abstract: The project is focused on the study of anti-thromotic effects of the flower extract of Gillardia pulchella and bark extract of Hymenaea martiana using k-carrageenan induced thrombosis method. To evaluate the anti-thrombotic activity of ethanolic extracts of Hymnenaea martiana and Gillardia pulchella, it is tested by phytochemical analysis, invitro and invivo models. Oral dosing of the plant extracts in different doses alleviates the thrombosis. This may be achieved by serum estimation of the haemoglobin, CRP, WBC, etc and histopathological study of the tail. The rats’ tails were dissected out from one animal of each group for histopathological examination for the estimation of parameters like thrombus, congestion in the vein, disruption of cellular matter and epithelial morphology. When the microscopy of the tail was done, it was found that thrombosis was healed with the plant extracts when compared to standard drug (heparin) . The study asserts that further reasearh needs to be taken on the benefits of Hymenaea martiana and Gillardia pulchella in Thrombosis. |
| Keywords: | Keywords: Thrombosis, Hymenaea martiana, Gillardia pulchella,K-Carrageenan, Heparin |
| Cite Article: | "INVITRO AND INVIVO PHARMACOLOGICAL MODELS FOR THROMBOLYTIC ACTIVITY IN HYMENAEA MARTIANA AND GILLARDIA PULCHELLA ETHANOLIC EXTRACTS USING K-CARRAGEENAN INDUCED THROMBOSIS", International Journal for Research Trends and Innovation (www.ijrti.org), ISSN:2455-2631, Vol.7, Issue 12, page no.81 - 97, December-2022, Available :http://www.ijrti.org/papers/IJRTI2212014.pdf |
| Downloads: | 000205253 |
| ISSN: |
2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID: IJRTI2212014
Registration ID:184728
Published In: Volume 7 Issue 12, December-2022
DOI (Digital Object Identifier):
Page No: 81 - 97 Country: HYDERABAD, TELANGANA, India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2212014 Published Paper PDF: https://www.ijrti.org/papers/IJRTI2212014 |
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ISSN: 2456-3315
Impact Factor: 8.14 and ISSN APPROVED,
Journal Starting Year (ESTD) : 2016
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