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International Journal for Research Trends and Innovation
International Peer Reviewed & Refereed Journals, Open Access Journal
ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
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Impact Factor : 8.14
Issue per Year : 12
Volume Published : 8
Issue Published : 90
Article Submitted : 9239
Article Published : 4707
Total Authors : 12260
Total Reviewer : 556
Total Countries : 88
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| Paper Title: | New UV Spectrophotometric method development and validation for the estimation of Sitagliptin and Glimepiride in pharmaceutical dosage forms and bulk drug |
| Authors Name: | DILLAN KUMAR , KUMARI KHUSHBOO , ASHU , SREENIVAS RAO T , Chandanam Sreedhar |
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IJRTI_184488
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| Published Paper Id: | IJRTI2210114 |
| Published In: | Volume 7 Issue 10, October-2022 |
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| Abstract: | New UV Spectrophotometric method has been developed for the simultaneous estimation of Sitagliptin phosphate and Glimepiride in pharmaceutical dosage forms and bulk drugs. The proposed method were based on the application of simultaneous equation .Absorbance maxima for Sitagliptin and Glimepiride were found to be 267nm and 225 nm respectively. The Calibration curves were linear with correlation coefficient of 0.9959 over the concentration range of 20-70µg/ml for Sitagliptin phosphate and 5-30µg/ml for Glimepiride and with correlation coefficient of 0.9969 The mean percent recovery was found to be 99.7and 100.1 for Sitagliptin phosphate and Glimepiride. The results of analysis were validated statistically. The proposed simple UV methods were rapid, accurate, precise and economical and can be used in the quality control of pharmaceutical formulations and routine laboratory analysis. |
| Keywords: | Sitagliptin, Glimepiride, UV Spectrophotometry, Linearity |
| Cite Article: | "New UV Spectrophotometric method development and validation for the estimation of Sitagliptin and Glimepiride in pharmaceutical dosage forms and bulk drug", International Journal of Science & Engineering Development Research (www.ijrti.org), ISSN:2455-2631, Vol.7, Issue 10, page no.949 - 955, October-2022, Available :http://www.ijrti.org/papers/IJRTI2210114.pdf |
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2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID: IJRTI2210114
Registration ID:184488
Published In: Volume 7 Issue 10, October-2022
DOI (Digital Object Identifier):
Page No: 949 - 955 Country: Bangalore, karnataka, India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2210114 Published Paper PDF: https://www.ijrti.org/papers/IJRTI2210114 |
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ISSN: 2456-3315
Impact Factor: 8.14 and ISSN APPROVED
Journal Starting Year (ESTD) : 2016
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