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International Journal for Research Trends and Innovation
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ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
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Impact Factor : 8.14
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| Paper Title: | Conventional Antibiotics from Actinomycetes: A mini review |
| Authors Name: | Krishna Kumar Das , Smaranika Pattnaik |
| Download E-Certificate: | Download |
| Author Reg. ID: |
IJRTI_183976
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| Published Paper Id: | IJRTI2209064 |
| Published In: | Volume 7 Issue 9, September-2022 |
| DOI: | |
| Abstract: | Actinomycetes are considered as a natural sink for production of antibiotics. Since many decades, the actinomycetes have drawn attention to mankind because of synthesis of bioactive metabolites. Among these antibiotics are considered to be the most potent biomolecules effective against infectious agents including bacteria, viruses and more of fungal strains. This mini review emphasized upon the antibacterial agents, synthesized in the power house of actinomycetes. The antibiotics belonging to class of aminoglycosides, macrolides, tetracyclines, penicillins and moreover, Rifampicin‘s are of utmost importance in clinical set up. The antibiotics have taken the throne to regulate the degree of infection cause by candidate bacteria including both Gram positive and Gram negatives. The tubercle bacteria are also inhibited by the antibiotic namely Rifampicin, which is a potential product of Streptomyces. The mechanism of action of each of antibiotic molecules is target oriented. The antibiotics are able to interact with Bacterial cell wall cross linkage enzymes, Ribosomes, RNA polymerases, protein synthesis events, thus killing the bacteria. Therefore, it may be concluded that this literature survey had inferred about the specific drug categories, synthesized from Actinomycetes and respective target oriented mechanism of action. It was also found that Actinomycetes are never ending source of bioactive compounds. Therefore, studies are mandate to reveal the Pandora‘s Box containing the bioactive antibiotics from the actinomycetal strains. |
| Keywords: | Actinomycetes, Antibiotics, Mechanism of action, Rifampicin, bioactive metabolites. |
| Cite Article: | "Conventional Antibiotics from Actinomycetes: A mini review", International Journal of Science & Engineering Development Research (www.ijrti.org), ISSN:2455-2631, Vol.7, Issue 9, page no.487 - 495, September-2022, Available :http://www.ijrti.org/papers/IJRTI2209064.pdf |
| Downloads: | 000205127 |
| ISSN: |
2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID: IJRTI2209064
Registration ID:183976
Published In: Volume 7 Issue 9, September-2022
DOI (Digital Object Identifier):
Page No: 487 - 495 Country: Sambalpur, Odisha, India Research Area: Biological Science Publisher : IJ Publication Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2209064 Published Paper PDF: https://www.ijrti.org/papers/IJRTI2209064 |
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ISSN: 2456-3315
Impact Factor: 8.14 and ISSN APPROVED,
Journal Starting Year (ESTD) : 2016
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