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International Journal for Research Trends and Innovation
International Peer Reviewed & Refereed Journals, Open Access Journal
ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
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Impact Factor : 8.14
Issue per Year : 12
Volume Published : 11
Issue Published : 118
Article Submitted : 21604
Article Published : 8531
Total Authors : 22438
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| Paper Title: | An Outline On Improving Solubility And Dissolution Rate In Solid Dispersion Technique |
| Authors Name: | Nikam Swati Prakash , Atish.B. Velhal , Prakash.D.Jadhav |
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| Author Reg. ID: |
IJRTI_183971
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| Published Paper Id: | IJRTI2209007 |
| Published In: | Volume 7 Issue 9, September-2022 |
| DOI: | |
| Abstract: | To improve dissolution of poorly water-soluble drugs and thus enhancing their bioavailability, the dispersion of one or more active pharmaceutical ingredient in a carrier at solid state is used. This process is known as solid dispersion. It has engrossed significant interest as an efficient means of improving the dissolution rate. Solid dispersions are being employed frequently to improve bioavailability of poorly soluble molecules by enhancing the rate and extent of dissolution in drug product development process. This review discussed the methods for solubility enhancement of poorly soluble drugs and the mechanism by which solubility and dissolution rate enhancement occurs in solid dispersion. The present article also discuss about the manufacturing methods for solubility enhancement, its mechanism and outcome of various low soluble drugs, applications, limitations of the solid dispersions. |
| Keywords: | Solid Dispersion, solubility enhancement mechanism, bioavailability. |
| Cite Article: | "An Outline On Improving Solubility And Dissolution Rate In Solid Dispersion Technique", International Journal for Research Trends and Innovation (www.ijrti.org), ISSN:2455-2631, Vol.7, Issue 9, page no.60 - 66, September-2022, Available :http://www.ijrti.org/papers/IJRTI2209007.pdf |
| Downloads: | 000205245 |
| ISSN: |
2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID: IJRTI2209007
Registration ID:183971
Published In: Volume 7 Issue 9, September-2022
DOI (Digital Object Identifier):
Page No: 60 - 66 Country: Satara, Maharashtra, India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2209007 Published Paper PDF: https://www.ijrti.org/papers/IJRTI2209007 |
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ISSN: 2456-3315
Impact Factor: 8.14 and ISSN APPROVED,
Journal Starting Year (ESTD) : 2016
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