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International Journal for Research Trends and Innovation
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ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
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Impact Factor : 8.14

Issue per Year : 12

Volume Published : 8

Issue Published : 85

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Paper Title: FORMULATION AND EVALUATION OF FAST DISSOLUTION TABLET OF DOXAZOSIN MESYLATE
Authors Name: Rewati Raman , Sandeep sahu , Ritesh jain , Suruchi prasad , Satish sahu
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IJRTI_183410
Published Paper Id: IJRTI2208023
Published In: Volume 7 Issue 8, August-2022
DOI:
Abstract: Tablet is the most widely used dosage form because of its convenience in terms of self-administration, compactness and ease in manufacturing. Patients often experience difficulty in swallowing conventional tablets when water is not available nearby. According to European pharmacopeia, these MDTs should dissolve in less than three minutes. The formulation is more useful for the bed ridden and patients who have the swallowing problem. Solid dispersion is one of the accepted approaches for dissolution enhancement. They are molecular mixtures of poor water-soluble drugs with hydrophilic carriers prepared by solvent evaporation and melting method. Doxazosin mesylate (DM), a quinazoline derivative, could be used in the treatment of mild to moderate hypertension and also in the management of symptomatic benign prostatic hyperplasia (BPH). In hypertensive patients, DM reduces the blood pressure by selective antagonizing the postsynaptic alpha1 adrenergic receptors
Keywords: mouth dissolving tablet, solid dispersion, doxazosin.
Cite Article: "FORMULATION AND EVALUATION OF FAST DISSOLUTION TABLET OF DOXAZOSIN MESYLATE", International Journal of Science & Engineering Development Research (www.ijrti.org), ISSN:2455-2631, Vol.7, Issue 8, page no.129 - 135, August-2022, Available :http://www.ijrti.org/papers/IJRTI2208023.pdf
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ISSN: 2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
Publication Details: Published Paper ID: IJRTI2208023
Registration ID:183410
Published In: Volume 7 Issue 8, August-2022
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Page No: 129 - 135
Country: Bilaspur, Chattisgarh, India
Research Area: Pharmacy
Publisher : IJ Publication
Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2208023
Published Paper PDF: https://www.ijrti.org/papers/IJRTI2208023
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ISSN: 2456-3315
Impact Factor: 8.14 and ISSN APPROVED
Journal Starting Year (ESTD) : 2016

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