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Phytosomes a little “cell-like structure” which is made up of a molecular complex of phospholipids with phytoconstituents. They serve as a link between traditional and novel formulations. Phytosomes, which are lipid-based nanocarriers, have a crucial function in strengthening the pharmacokinetic and pharmacodynamic properties of herbal-derived polyphenolic compounds, making this nanotechnology a promising tool for the development of novel formulations. Bioavailability is a significant concern in improving bio-efficacy in the transport of dietary phytochemicals. Phospholipids work as emulsifiers by increasing the hydrophilicity and lipophilicity of phytoconstituents. For enhanced absorption and bioavailability of natural phytoconstituents, a balance of hydrophilicity (helps phytoconstituents dissolve in digestive fluids) and lipophilicity (helps phytoconstituents to penetrate lipid-based cell membranes) is essential. The enormous potential of emerging nanotechnology in the delivery of bioactive phytochemicals is examined, with a special focus on phytosomes as a novel lipid-based nanocarrier. The current review represents an overview of the vesicular system and its application, with emphasis on formulation consideration and characterization of the phyto-phospholipid complex.
Keywords:
Phytosomes, Bioavailability, Phospholipid, Phytoconstituents, Novel Drug Delivery Systems.
Cite Article:
"Phyto-phospholipid Complexes (Phytosomes): A Novel Option to Enhance the Bioavailability of Plants` Pharmacologically Active Chemical Components", International Journal of Science & Engineering Development Research (www.ijrti.org), ISSN:2455-2631, Vol.7, Issue 7, page no.1399 - 1410, July-2022, Available :http://www.ijrti.org/papers/IJRTI2207251.pdf
Downloads:
000204943
ISSN:
2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator