Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.14 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI)
Exploration of nanomaterials delivers good synergism between nanoscience and nanotechnology endeavors new frontiers in plethora of biomedical applications. Multifunctional nanoparticles are now widely exploited and proven their versatility as drug delivery conveyance in cancer therapeutics area. Herein in this proposed work a synthesis of folic acid (FA) functionalized rare earth metal oxide has been carried out to as nanotherapeutics in cancer therapy and diagnostic field. Functionalization of FA onto cerium oxide (CeO2) enables enhanced cellular uptake in cancer cells confirmed from DAPI micrographs. The cytomorphological architecture and cell migration assays of the cancer cells has also been monitored using scanning electron and optical micrographs respectively. The findings implying the inhibition of cancerous cells migration upon treatment. Further the nanotherapeutic modality of these nanoparticles was evaluated and screened in human colorectal carcinoma cells signifying the anticancer efficacy of the nanoparticles.
Keywords:
Nanoparticle, folic acid, nanoceria, cytomorphology, apoptosis, cancer therapy
Cite Article:
"Fabrication of functionalized nanoceria: A nanotheranostic avenue towards cancer therapy", International Journal of Science & Engineering Development Research (www.ijrti.org), ISSN:2455-2631, Vol.7, Issue 7, page no.1440 - 1444, July-2022, Available :http://www.ijrti.org/papers/IJRTI2207226.pdf
Downloads:
000204922
ISSN:
2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator