 |
International Journal for Research Trends and Innovation
International Peer Reviewed & Refereed Journals, Open Access Journal
ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.14 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI)
|
Issue: March 2026
Volume 11 | Issue 3
Review Result and Publication of Paper within : 2-3 days
Click Here For more DetailsFor Authors
Forms / Download
Published Issue Details
Editorial Board
Other IMP Links
Facts & Figure
Impact Factor : 8.14
Issue per Year : 12
Volume Published : 11
Issue Published : 118
Article Submitted : 21545
Article Published : 8519
Total Authors : 22414
Total Reviewer : 805
Total Countries : 159
Indexing Partner
Licence
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License
|
Published Paper Details
|
|
| Paper Title: | Detection of Pvl gene for the presence of leukocidin among clinical isolates of staphylococcus aureus |
| Authors Name: | Pavithra K , Mr.Gopinath , Dr. M.S.Niveditha |
| Download E-Certificate: | Download |
| Author Reg. ID: |
IJRTI_181135
|
| Published Paper Id: | IJRTI2002012 |
| Published In: | Volume 5 Issue 2, February-2020 |
| DOI: | |
| Abstract: | Aim:- Detection of Pvl gene for the presence of leukocidin among clinical isolates of staphylococcus aureus Background:-PVL and γ -haemolysin are considered to be members of a toxin family known as synergohymenotropic toxins, as they act on cell membranes by the synergy of two proteins that form a pore. Only 2% of S. aureus isolates produce PVL, while γ -haemolysin is produced by more than 99% of S. aureus isolates. PVL is the most leukocytolytic toxin in the family, however it does not exhibits no haemolytic activity on human erythrocytes. A sum of 20 clinical isolates of S. aureus were subjected to antibiotic sensitivity pattern followed by the detection of pvl gene by PCR. We have observed increased resistance to most of the routinely used antibiotics and 10% of our isolates found to have pvl gene. As this gene is directly associated with skin and soft tissue infections by S. aureus, our two isolates may even cause such infections, although none of these strains were not obtained from cutaneous lesions. Panton–Valentine leukocidin (PVL) is one of many toxins associated with S. aureus infection. Because it can be found in virtually all CA-MRSA strains that cause soft-tissue infections, it was long described as a key virulence factor, allowing the bacteria to target and kill specific white blood cells known as neutrophils. This view was challenged, however, when it was shown that removal of PVL from the two major epidemic CA-MRSA strains resulted in no loss of infectivity or destruction of neutrophils in a mouse model. Materials and Method:- These antibiotics were procured from Himedia, Mumbai. This was performed by Kirby-bauer disc diffusion method as per CLSI guidelines. Conclusion:- The pathogenicity of Staphylococcus aureus depends on various bacterial surface components and extracellular proteins. uggests that the Panton-Valentine leukocidin (PVL) is 1 such virulence factor that has a major role in pathogenicity. |
| Keywords: | Staphylococcus aureus, Pvl gene, PCR, Leukocidin ,Haemolysin. |
| Cite Article: | "Detection of Pvl gene for the presence of leukocidin among clinical isolates of staphylococcus aureus", International Journal for Research Trends and Innovation (www.ijrti.org), ISSN:2455-2631, Vol.5, Issue 2, page no.60 - 65, February-2020, Available :http://www.ijrti.org/papers/IJRTI2002012.pdf |
| Downloads: | 000205381 |
| ISSN: |
2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
| Publication Details: |
Published Paper ID: IJRTI2002012
Registration ID:181135
Published In: Volume 5 Issue 2, February-2020
DOI (Digital Object Identifier):
Page No: 60 - 65 Country: Chennai, Tamil Nadu, India Research Area: Biological Science Publisher : IJ Publication Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2002012 Published Paper PDF: https://www.ijrti.org/papers/IJRTI2002012 |
| Share Article: | |
|
Click Here to Download This Article |
|
| Article Preview | |
|
|
|
Major Indexing from www.ijrti.org
| Google Scholar | ResearcherID Thomson Reuters | Mendeley : reference manager | Academia.edu |
| arXiv.org : cornell university library | Research Gate | CiteSeerX | DOAJ : Directory of Open Access Journals |
| DRJI | Index Copernicus International | Scribd | DocStoc |
ISSN Details
 |
 |
|
ISSN: 2456-3315
Impact Factor: 8.14 and ISSN APPROVED,
Journal Starting Year (ESTD) : 2016
DOI (A digital object identifier)
| Providing A digital object identifier by DOI.ONE How to Get DOI? |
Conference
Open Access License Policy
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License
Important Details
Join RMS/Earn 300
WhatsApp
Click Here
Click Here
Indexing Partner |
|||
| Copyright © 2026 - All Rights Reserved - IJRTI | |||