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ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
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Impact Factor : 8.14

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Paper Title: An insight into hair follicle via epigenetic modification and molecular docking: A review
Authors Name: Arun R. Nair , Dr. Mahavir Yadav , Prof. Archana Tiwari
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Published Paper Id: IJRTI1808028
Published In: Volume 3 Issue 8, August-2018
Abstract: Hair follicle, a mini-organ developed in the epithelial layer is one of the complex structural and functional unit of the hair growth. In this review, we discuss about the Androgenetic alopecia, where miniature of the hair takes place converting testosterone to dihydrotestosterone by 5-alpha reductase. We also discuss about LHX2, which is responsible for the initiation of anagen phase of hair growth. Prostaglandin D2 synthase converts PGH2 to PGD2, which leads to the hair loss. Few key players in the epigenetic modification process like DNMT1, DNMT3a, DNMT3b, DNMT3L and TETs group of proteins, which gives structural stability to the gene and expression, play an important role in hair growth. We review the previous and future possibilities of drug design for preventing hair loss with the help of molecular docking performed on these players as well as on Prostaglandin D2 synthase.
Cite Article: "An insight into hair follicle via epigenetic modification and molecular docking: A review", International Journal of Science & Engineering Development Research (www.ijrti.org), ISSN:2455-2631, Vol.3, Issue 8, page no.165 - 171, August-2018, Available :http://www.ijrti.org/papers/IJRTI1808028.pdf
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ISSN: 2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
Publication Details: Published Paper ID: IJRTI1808028
Registration ID:180346
Published In: Volume 3 Issue 8, August-2018
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Page No: 165 - 171
Country: bhopal, Madhya Pradesh, India
Research Area: Engineering
Publisher : IJ Publication
Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI1808028
Published Paper PDF: https://www.ijrti.org/papers/IJRTI1808028
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ISSN: 2456-3315
Impact Factor: 8.14 and ISSN APPROVED
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