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ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
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Impact Factor : 8.14

Issue per Year : 12

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Paper Title: Botanical interventions in cardiovascular health
Authors Name: Sakshi G. Gawde , Dr. Mandar Mulik
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IJRTI_205179
Published Paper Id: IJRTI2508015
Published In: Volume 10 Issue 8, August-2025
DOI:
Abstract: Cardiovascular diseases (CVDs) remain the leading cause of morbidity and mortality worldwide, driven by interconnected mechanisms such as oxidative stress, chronic inflammation, endothelial dysfunction, and metabolic disturbances. While pharmacological therapies form the backbone of CVD management, their long-term use is often limited by adverse effects and incomplete prevention of disease progression. In recent years, botanical interventions have gained considerable attention for their multifaceted cardioprotective effects and favourable safety profiles. This review explores the pathogenesis of CVDs and examines a range of medicinal plants, including Moringa oleifera, Curcuma longa, Camellia sinensis, Allium sativum, Berberis spp., Brassica vegetables, Panax ginseng, and Ginkgo biloba. The bioactive constituents of these botanicals, such as flavonoids, alkaloids, polyphenols, and terpenoids, exhibit antioxidant, anti-inflammatory, antihypertensive, lipid-lowering, vasodilatory, and antithrombotic activities. Mechanistic insights highlight their potential to modulate oxidative pathways, reduce pro-inflammatory cytokine expression, improve endothelial function, and regulate lipid metabolism. Although preliminary clinical studies support their cardiovascular benefits, challenges such as standardisation, herb–drug interactions, and limited large-scale trials hinder their integration into modern therapeutics. Future research should focus on rigorous clinical validation and standardised formulations to ensure safe and effective incorporation of botanicals into cardiovascular disease prevention and management strategies.
Keywords: Botanical interventions; cardiovascular diseases; herbal medicine; phytochemicals; antioxidant; anti-inflammatory; endothelial dysfunction; lipid lowering; traditional medicine; complementary therapy
Cite Article: "Botanical interventions in cardiovascular health", International Journal of Science & Engineering Development Research (www.ijrti.org), ISSN:2455-2631, Vol.10, Issue 8, page no.a83-a92, August-2025, Available :http://www.ijrti.org/papers/IJRTI2508015.pdf
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ISSN: 2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
Publication Details: Published Paper ID: IJRTI2508015
Registration ID:205179
Published In: Volume 10 Issue 8, August-2025
DOI (Digital Object Identifier):
Page No: a83-a92
Country: Dombivli, Thane, Maharashtra, India
Research Area: Pharmacy
Publisher : IJ Publication
Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2508015
Published Paper PDF: https://www.ijrti.org/papers/IJRTI2508015
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ISSN: 2456-3315
Impact Factor: 8.14 and ISSN APPROVED, Journal Starting Year (ESTD) : 2016

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