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International Journal for Research Trends and Innovation
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ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
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Impact Factor : 8.14
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| Paper Title: | Simultaneous Estimation of UHPLC Method Development and Validation for Kopexil and Minoxidil in Bulk and Topical Solution |
| Authors Name: | Bharani Krishnika P , Nalini C N , Vijayakumar R |
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IJRTI_189889
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| Published Paper Id: | IJRTI2405058 |
| Published In: | Volume 9 Issue 5, May-2024 |
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| Abstract: | Kopexil and Minoxidil belongs to a class of vasodilator drug used to treat Alopecia. A simple, accurate, precise method was developed for the simultaneous estimation of the Minoxidil & Kopexil in solid dosage form by using Ultra high performance liquid chromatography (UHPLC). Retention time of Minoxidil was found 2.359 min & Kopexil was found 3.195 min. % RSD of the Minoxidil was found 0.15% & Kopexil was found 0.71%. % Assay was obtained as 100.09% for Minoxidil & 100.38% Kopexil. Regression equation of Minoxidil y = 145.3647x + 56.8594 R² = 1.0000 & Kopexil is y = 0.0789x + 0.0561 R² = 1.0000. Retention times were decreased and that run time was decreased, so the method developed was simple and economical that can be adopted in regular Quality control test in Industries. |
| Keywords: | Minoxidil, Kopexil, UHPLC, Topical solution. |
| Cite Article: | "Simultaneous Estimation of UHPLC Method Development and Validation for Kopexil and Minoxidil in Bulk and Topical Solution", International Journal of Science & Engineering Development Research (www.ijrti.org), ISSN:2455-2631, Vol.9, Issue 5, page no.398 - 404, May-2024, Available :http://www.ijrti.org/papers/IJRTI2405058.pdf |
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2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID: IJRTI2405058
Registration ID:189889
Published In: Volume 9 Issue 5, May-2024
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Page No: 398 - 404 Country: Chennai, Tamilnadu, India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2405058 Published Paper PDF: https://www.ijrti.org/papers/IJRTI2405058 |
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ISSN: 2456-3315
Impact Factor: 8.14 and ISSN APPROVED,
Journal Starting Year (ESTD) : 2016
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