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International Journal for Research Trends and Innovation
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ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
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Volume 10 | Issue 12
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Impact Factor : 8.14
Issue per Year : 12
Volume Published : 10
Issue Published : 115
Article Submitted : 19440
Article Published : 8041
Total Authors : 21252
Total Reviewer : 769
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| Paper Title: | Comparative assessment of safety and effectiveness of metformin glimepiride and metformin vildagliptin in Type 2 Diabetes Mellitus patients |
| Authors Name: | Harilekshmi C K , Dr.Blessy K George , Nafhathulla , Dr.Balakeshwa Ramaiah |
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IJRTI_188707
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| Published Paper Id: | IJRTI2312087 |
| Published In: | Volume 8 Issue 12, December-2023 |
| DOI: | |
| Abstract: | Diabetes, a prevalent chronic condition that require ongoing care to avoid complications. The mainstay of diabetic treatment, metformin is frequently enhanced in effectiveness by being taken with other drugs such as glimepiride or vildagliptin.Vildagliptin,a DPP4 inhibitor ,increase insulin secretion and controls blood glucose levels, whereas glimepiride, a sulphonylureas accelerates the release of insulin. The present study insight into compare the safety and effectiveness of Metformin glimepiride versus Metformin vildagliptin in the treatment of type 2 diabetic patients. The study was single centered, prospective randomized, comparative and observational study carried out for six months. Totally 50 patients were enrolled for this study who met inclusion criteria and are divided equally into 2 groups, Group A (Metformin glimepiride) and Group B(Metformin vildagliptin).To compare the safety and effectiveness of both groups by assessing patient glucose level, demographic details, dose,frequency,Adverse effect.The study shows that there was a significant reduction in the p values of FBS,RBS,HBAIC of both groups. Hence the study concluded that both groups work effectively in a same manner and Metformin vildagliptin resulted in better adverse event profile with lower risk of hypoglycemia. |
| Keywords: | Type 2 diabetes, Metformin, Vildagliptin, Glimepiride, FBS,RBS, HbA1C, ADR’s |
| Cite Article: | "Comparative assessment of safety and effectiveness of metformin glimepiride and metformin vildagliptin in Type 2 Diabetes Mellitus patients", International Journal of Science & Engineering Development Research (www.ijrti.org), ISSN:2455-2631, Vol.8, Issue 12, page no.619 - 630, December-2023, Available :http://www.ijrti.org/papers/IJRTI2312087.pdf |
| Downloads: | 000205158 |
| ISSN: |
2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID: IJRTI2312087
Registration ID:188707
Published In: Volume 8 Issue 12, December-2023
DOI (Digital Object Identifier):
Page No: 619 - 630 Country: Bengaluru, Karnataka, India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2312087 Published Paper PDF: https://www.ijrti.org/papers/IJRTI2312087 |
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ISSN: 2456-3315
Impact Factor: 8.14 and ISSN APPROVED,
Journal Starting Year (ESTD) : 2016
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