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ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
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Impact Factor : 8.14
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| Paper Title: | Current Impact of Bioinformatics Based Approaches in Providing Solutions against Rheumatoid Arthritis |
| Authors Name: | Priyangulta Beck , Hewanti Kumari, Sweety Guria Rani , Purbasha Pati, Sadaf Naaz , Kumari Surekha Mahto, Shekhar Marandi, Anant Kumar Mehta , Shristi Kumari, Agatha Sylvia Khalko, Soma Roy, Mukesh Nitin |
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IJRTI_182884
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| Published Paper Id: | IJRTI2207118 |
| Published In: | Volume 7 Issue 7, July-2022 |
| DOI: | |
| Abstract: | Rheumatoid Arthritis (RA) is a chronic autoimmune inflammatory disease characterized by symmetric synovial joint inflammation, with an incidence of 0.5-1 percent in prosperous nation. It occurs due to abnormal activity in immune response that encourages our immune system to attack its own cells and starts attacking the lining of joints. Occurrence of chronic inflammation is related to the significant involvement of vital inflammatory cytokines and TNF alpha (TNF- α). Maximum patients develop RA due to environmental, genetic and hormonal activities. 50% of RA patients develop RA due to genetic factors. It affects joints in palm, knees, wrists and several organs like skin, lungs, blood vessels, kidneys and heart. The exact cause of RA is still not found. Various types of drugs are implemented to treat rheumatoid arthritis-like non-steroidal anti-inflammatory drugs (NSAIDs), corticosteroids, Disease-Modifying Anti-Rheumatic Drugs (DMARDs). Past few decades, more than 60 molecular docking tools have been discovered to study the different properties of RA. Few of them are- Next-generation sequencing (NGS) and the omics approaches (transcriptomics, epigenomics and genomics), dispense novel views of genome-wide association studies (GWAS). Bioinformatics has also taken accurate steps together with genomics and docking studies to support the drug discovery in treating rheumatoid arthritis. |
| Keywords: | Rheumatoid arthritis, Docking tools, Omics, GEO, NGS |
| Cite Article: | "Current Impact of Bioinformatics Based Approaches in Providing Solutions against Rheumatoid Arthritis", International Journal of Science & Engineering Development Research (www.ijrti.org), ISSN:2455-2631, Vol.7, Issue 7, page no.805 - 812, July-2022, Available :http://www.ijrti.org/papers/IJRTI2207118.pdf |
| Downloads: | 000204907 |
| ISSN: |
2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID: IJRTI2207118
Registration ID:182884
Published In: Volume 7 Issue 7, July-2022
DOI (Digital Object Identifier):
Page No: 805 - 812 Country: -, -, - Research Area: Engineering Publisher : IJ Publication Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2207118 Published Paper PDF: https://www.ijrti.org/papers/IJRTI2207118 |
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ISSN: 2456-3315
Impact Factor: 8.14 and ISSN APPROVED,
Journal Starting Year (ESTD) : 2016
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