International Journal for Research Trends and Innovation
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ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
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Impact Factor : 8.14

Issue per Year : 12

Volume Published : 9

Issue Published : 93

Article Submitted : 9866

Article Published : 5018

Total Authors : 13224

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Authors Name: Hazira Bin Ahmed
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Published Paper Id: IJRTI2008019
Published In: Volume 5 Issue 8, August-2020
Abstract: Background: The present study aimed to develop an Ethosomal formulation for topical delivery of Nabumetone to enhance the water solubility as well as the permeability of the drug.The ethosomes was prepared by cold method, ethanol is used as a penetration enhancer.F1 to F12 different formulation of ethosomes are prepared and characterized for size and shape analysis, entrapment efficacy. Carbopol 934 is used as a gelling agent. The prepared formulation was evaluated for spreadability, in vitro diffusion study, in vivo skin permeation study. Nabumetone is NSAID belongs bio pharmaceutics classification system (BCS) class II drug, widely used in the treatment of osteoarthritis and rheumatoid arthritis. The most frequently reported adverse reactions for the drug involve a disturbance in the gastrointestinal tract, diarrhea, dyspepsia, and abdominal pain.
Keywords: Nabumetone, Ethosomes, topical delivery, Phospholipid, Anti-inflammatory activity.
Cite Article: "PREPARATION AND CHARACTERIZATION OF NABUMETONE ETHOSOMAL GEL", International Journal of Science & Engineering Development Research (www.ijrti.org), ISSN:2455-2631, Vol.5, Issue 8, page no.103 - 106, August-2020, Available :http://www.ijrti.org/papers/IJRTI2008019.pdf
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ISSN: 2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
Publication Details: Published Paper ID: IJRTI2008019
Registration ID:181338
Published In: Volume 5 Issue 8, August-2020
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Page No: 103 - 106
Research Area: Pharmacy
Publisher : IJ Publication
Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2008019
Published Paper PDF: https://www.ijrti.org/papers/IJRTI2008019
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ISSN: 2456-3315
Impact Factor: 8.14 and ISSN APPROVED
Journal Starting Year (ESTD) : 2016

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