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International Journal for Research Trends and Innovation
International Peer Reviewed & Refereed Journals, Open Access Journal
ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
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Issue: May 2022
Volume 7 | Issue 5
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Impact Factor : 8.14
Issue per Year : 12
Volume Published : 7
Issue Published : 72
Article Submitted : 2681
Article Published : 1604
Total Authors : 4237
Total Reviewer : 523
Total Countries : 29
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Paper Title: | Preparation and evaluation of Tavaborole solid lipid nano particles topical gel |
Authors Name: | Ayesha Banu , Dr.Abdul Mannan |
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IJRTI_181300
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Published Paper Id: | IJRTI2007008 |
Published In: | Volume 5 Issue 7, August-2020 |
DOI: | |
Abstract: | The work is aimed to formulate nanodispersion of tavaborole solid lipid nanoparticles (SLNs) gel by using a high shear homogenization technique using ultrasonication method. Which is preferably utilized in case of anti-fungal nail infection (onchomyosisi) as an effective drug. (1) The nine different formulations of Tavaborole SLNs (SLN1-SLN9) were prepared using solid and liquid lipid with compritol888ATO (2) and cholesterol in several Concentration by the ultrasonication method. (3) The formulations were also characterized for particle size, entrapment efficiency, drug loading and depression in freezing point. The results: The DSC, FTIR analyses were performed to characterize the state of drug and lipid modification. Shape and surface morphology were determined by SEM which showed spherical shapes of the formulations. Further the formulation was evaluated for in vitro drug permeability Study, religiously properties, skin irritation, Pharmacodynamic and stability studies. (4) |
Keywords: | Tavaborole,High shear homogenization,Ultrasonication Method,Topical gel |
Cite Article: | "Preparation and evaluation of Tavaborole solid lipid nano particles topical gel", International Journal of Science & Engineering Development Research (www.ijrti.org), ISSN:2455-2631, Vol.5, Issue 7, page no.63 - 66, July-2020, Available :http://www.ijrti.org/papers/IJRTI2007008.pdf |
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2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID: IJRTI2007008
Registration ID:181300
Published In: Volume 5 Issue 7, August-2020
DOI (Digital Object Identifier):
Page No: 63 - 66 Country: Hyderabad, Other, India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2007008 Published Paper PDF: https://www.ijrti.org/papers/IJRTI2007008 |
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ISSN: 2456-3315
Impact Factor: 8.14 and ISSN APPROVED
Journal Starting Year (ESTD) : 2016
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