ugc approved journal list IJRTI Research Journal
International Journal for Research Trends and Innovation
An International Open Access Journal | UGC and ISSN Approved
Impact Factor: 4.87

Call For Paper

Issue: October 2018

Volume 3 | Issue 10

Impact Factor: 4.87

Submit Paper Online

Click Here For more Details

For Authors

Forms / Download

Editorial Board

Subscribe IJRTI

Facts & Figure

Impact Factor : 4.87

Issue per Year : 12

Volume Published : 3

Issue Published : 29

Article Submitted : 1206

Article Published : 741

Total Authors : 1982

Total Reviewer : 503

Total Pages : 134

Total Countries : 10

Visitor Counter


Indexing Partner

Published Paper Details
Paper Title: An insight into hair follicle via epigenetic modification and molecular docking: A review
Authors Name: Arun R. Nair , Dr. Mahavir Yadav , Prof. Archana Tiwari
Unique Id: IJRTI1808028
Published In: Volume 3 Issue 8, August-2018
Abstract: Hair follicle, a mini-organ developed in the epithelial layer is one of the complex structural and functional unit of the hair growth. In this review, we discuss about the Androgenetic alopecia, where miniature of the hair takes place converting testosterone to dihydrotestosterone by 5-alpha reductase. We also discuss about LHX2, which is responsible for the initiation of anagen phase of hair growth. Prostaglandin D2 synthase converts PGH2 to PGD2, which leads to the hair loss. Few key players in the epigenetic modification process like DNMT1, DNMT3a, DNMT3b, DNMT3L and TETs group of proteins, which gives structural stability to the gene and expression, play an important role in hair growth. We review the previous and future possibilities of drug design for preventing hair loss with the help of molecular docking performed on these players as well as on Prostaglandin D2 synthase.
Keywords:
Cite Article: "An insight into hair follicle via epigenetic modification and molecular docking: A review", International Journal of Science & Engineering Development Research (www.ijrti.org), ISSN:2455-2631, Vol.3, Issue 8, page no.165 - 171, August-2018, Available :http://www.ijrti.org/papers/IJRTI1808028.pdf
Downloads: 00062
Publication Details: Published Paper ID: IJRTI1808028
Registration ID:180346
Published In: Volume 3 Issue 8, August-2018
DOI (Digital Object Identifier):
ISSN Number: 2456 - 3315
Share Article:

Click Here to Download This Article

Article Preview



Major Indexing from www.ijrti.org
Google Scholar ResearcherID Thomson Reuters Mendeley : reference manager Academia.edu
arXiv.org : cornell university library Research Gate CiteSeerX DOAJ : Directory of Open Access Journals
DRJI Index Copernicus International Scribd DocStoc

ISSN Details

DOI (A digital object identifier)



Providing A digital object identifier by DOI
How to GET DOI and Hard Copy Related

RMS

Conference Proposal

Latest News / Updates

Open Access License Policy

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License

Creative Commons License This material is Open Knowledge This material is Open Data This material is Open Content

Important Details

Social Media

Untitled Document