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International Journal for Research Trends and Innovation
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Volume 3 | Issue 12

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Impact Factor : 4.87

Issue per Year : 12

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Paper Title: Review on Autophagy: Mechanism of Cell House Keeping
Authors Name: Monika Mehta , Dr. Naga Rathna Supriya
Unique Id: IJRTI1807031
Published In: Volume 3 Issue 7, July-2018
Abstract: Autophagy is a normal process occurring in our body to maintain cellular homeostasis but it is up-regulated during stress condition inside the cell. It is a highly conserved and regulated process which involves lysosomal mediated degradation of damaged and faulty components and recycle or reuses when needed. Despite its role in degradation it has its connection with various diseases like cancer, neurodegeneration, muscle disease, liver disease, cardiac disease and many more. The process of autophagy consist of various steps and each step is regulated by various regulatory proteins which is found to be deleted or mutated when present in disease. This review has focus on the process of autophagy and its regulation along with its connection with various diseases. Few examples might be paving a way for innovative remedy for treating many diseases and disorders.
Keywords: Autophagy, cancer, neurodegeneration, muscle disease, liver disease, cardiac disease.
Cite Article: "Review on Autophagy: Mechanism of Cell House Keeping", International Journal of Science & Engineering Development Research (www.ijrti.org), ISSN:2455-2631, Vol.3, Issue 7, page no.204 - 211, July-2018, Available :http://www.ijrti.org/papers/IJRTI1807031.pdf
Downloads: 000669
Publication Details: Published Paper ID: IJRTI1807031
Registration ID:180361
Published In: Volume 3 Issue 7, July-2018
DOI (Digital Object Identifier):
ISSN Number: 2456 - 3315
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